ENSDARG00000098856


Danio rerio

Features
Gene ID: ENSDARG00000098856
  
Biological name :RYR2
  
Synonyms : ryanodine receptor 2 / RYR2
  
Possible biological names infered from orthology : E9Q401 / Q92736 / ryanodine receptor 2, cardiac
  
Species: Danio rerio
  
Chr. number: 12
Strand: 1
Band:
Gene start: 47162456
Gene end: 47456979
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000134587
Ensembl peptide - ENSDARP00000145486
Ensembl peptide - ENSDARP00000148885
Ensembl peptide - ENSDARP00000151291
Ensembl peptide - ENSDARP00000155998
swissprot - A0A0G2KQB9
Ensembl - ENSDARG00000098856
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RYR2ENSGALG00000010812Gallus gallus
 RYR2ENSG00000198626Homo sapiens
 Ryr2ENSMUSG00000021313Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ryr1a / ryanodine receptor 1a (skeletal) / RYR1* / P21817* / E9PZQ0* / ryanodine receptor 1*ENSDARG0000001142264
ryr1b / ryanodine receptor 1b (skeletal) / RYR1* / P21817* / ryanodine receptor 1*ENSDARG0000002379764
ryr2b / ryanodine receptor 2b (cardiac)ENSDARG0000000370663
ryr3 / ryanodine receptor 3 / A2AGL3* / Q15413*ENSDARG0000007133163
itpr1a / inositol 1,4,5-trisphosphate receptor, type 1a / ITPR1* / P11881* / Q14643* / inositol 1,4,5-trisphosphate receptor type 1*ENSDARG0000001465513
itpr1b / inositol 1,4,5-trisphosphate receptor, type 1b / ITPR1* / P11881* / Q14643* / inositol 1,4,5-trisphosphate receptor type 1*ENSDARG0000007414913
itpr3 / inositol 1,4,5-trisphosphate receptor, type 3 / P70227* / Q14573*ENSDARG0000006174112
itpr2 / inositol 1,4,5-trisphosphate receptor, type 2 / Q14571* / Q9Z329*ENSDARG000000119099
CABZ01083778.1ENSDARG000001154245
FO834850.1 / ITPR2* / Q14571* / inositol 1,4,5-trisphosphate receptor type 2*ENSDARG000001112612


Protein motifs (from Interpro)
Interpro ID Name
 IPR000699  RIH domain
 IPR001870  B30.2/SPRY domain
 IPR002048  EF-hand domain
 IPR003032  Ryanodine receptor Ryr
 IPR003877  SPRY domain
 IPR005821  Ion transport domain
 IPR009460  Ryanodine Receptor TM 4-6
 IPR011992  EF-hand domain pair
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR013333  Ryanodine receptor
 IPR013662  RyR/IP3R Homology associated domain
 IPR014821  Inositol 1,4,5-trisphosphate/ryanodine receptor
 IPR015925  Ryanodine receptor-related
 IPR016093  MIR motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006874 cellular calcium ion homeostasis IEA
 biological_processGO:0051209 release of sequestered calcium ion into cytosol IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005219 ryanodine-sensitive calcium-release channel activity IEA
 molecular_functionGO:0005262 calcium channel activity IEA
 molecular_functionGO:0005509 calcium ion binding IBA


Pathways (from Reactome)
Pathway description
Stimuli-sensing channels
Ion homeostasis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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