ENSDARG00000099732


Danio rerio

Features
Gene ID: ENSDARG00000099732
  
Biological name :gfra1a
  
Synonyms : gdnf family receptor alpha 1a / gfra1a
  
Possible biological names infered from orthology : GDNF family receptor alpha 1 / GFRA1 / P56159 / P97785
  
Species: Danio rerio
  
Chr. number: 13
Strand: -1
Band:
Gene start: 20392656
Gene end: 20519001
  
Corresponding Affymetrix probe sets: Dr.21002.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000129877
Ensembl peptide - ENSDARP00000141672
swissprot - A0A0H2UKX5
swissprot - B8JME8
ZFIN ID - ZDB-GENE-010226-2
Ensembl - ENSDARG00000099732
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GFRA1ENSGALG00000009173Gallus gallus
 GFRA1ENSG00000151892Homo sapiens
 Gfra1ENSMUSG00000025089Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gfra1b / gdnf family receptor alpha 1b / GFRA1* / P56159* / P97785* / GDNF family receptor alpha 1*ENSDARG0000010256474
gfra2b / GDNF family receptor alpha 2b / GFRA2* / O00451* / O08842* / GDNF family receptor alpha 2*ENSDARG0000004401548
gfra4a / GDNF family receptor alpha 4a / GFRA4* / Q9GZZ7* / Q9JJT2* / GDNF family receptor alpha 4*ENSDARG0000005665147
gfra2a / GDNF family receptor alpha 2a / GFRA2* / O00451* / O08842* / GDNF family receptor alpha 2*ENSDARG0000004272347
gfra4b / GDNF family receptor alpha 4b / GFRA4* / Q9GZZ7* / Q9JJT2* / GDNF family receptor alpha 4*ENSDARG0000007458244
gfra3 / GDNF family receptor alpha 3 / O35118* / O60609*ENSDARG0000008770430


Protein motifs (from Interpro)
Interpro ID Name
 IPR003438  Glial cell line-derived neurotrophic factor receptor
 IPR003503  Glial cell line-derived neurotrophic factor receptor, alpha 1
 IPR016017  GDNF/GAS1
 IPR017372  Glial cell line-derived neurotrophic factor receptor, alpha 1/2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0000186 activation of MAPKK activity IEA
 biological_processGO:0048484 enteric nervous system development IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046983 protein dimerization activity IDA


Pathways (from Reactome)
Pathway description
RAF/MAP kinase cascade
RET signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0005775 enteric neuron enteric neuron decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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