ENSDARG00000099960


Danio rerio

Features
Gene ID: ENSDARG00000099960
  
Biological name :elovl1a
  
Synonyms : elovl1a / ELOVL fatty acid elongase 1a
  
Possible biological names infered from orthology : Elongation of very long chain fatty acids protein 1 / ELOVL1 / ELOVL fatty acid elongase 1 / Q9BW60 / Q9JLJ5
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 19163965
Gene end: 19215112
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000139010
Ensembl peptide - ENSDARP00000141395
Ensembl peptide - ENSDARP00000138121
NCBI entrez gene - 449816     See in Manteia.
RefSeq - NM_001005989
RefSeq Peptide - NP_001005989
swissprot - A0A0R4IY97
swissprot - Q5XJ87
ZFIN ID - ZDB-GENE-041010-66
Ensembl - ENSDARG00000099960
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ELOVL1ENSGALG00000009988Gallus gallus
 ELOVL1ENSG00000066322Homo sapiens
 Elovl1ENSMUSG00000006390Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
elovl1b / ELOVL fatty acid elongase 1b / Q9JLJ5* / ELOVL1* / Q9BW60* / ELOVL fatty acid elongase 1* / Elongation of very long chain fatty acids protein 1 *ENSDARG0000010373566
elovl7a / ELOVL fatty acid elongase 7a / A1L3X0* / ELOVL7* / Q9D2Y9* / ELOVL fatty acid elongase 7* / Elongation of very long chain fatty acids protein 7 *ENSDARG0000006927948
elovl4b / ELOVL fatty acid elongase 4b / Q9GZR5* / ELOVL4* / Q9EQC4* / ELOVL fatty acid elongase 4* / Elongation of very long chain fatty acids protein 4 *ENSDARG0000002749537
elovl4a / ELOVL fatty acid elongase 4a / Q9GZR5* / ELOVL4* / Q9EQC4* / ELOVL fatty acid elongase 4* / Elongation of very long chain fatty acids protein 4 *ENSDARG0000000677336
elovl8b / ELOVL fatty acid elongase 8bENSDARG0000005736535
elovl8a / ELOVL fatty acid elongase 8aENSDARG0000006855134
elovl5 / ELOVL fatty acid elongase 5 / Q8BHI7* / Q9NYP7* / Elongation of very long chain fatty acids protein 5 *ENSDARG0000000497931
elovl2 / ELOVL fatty acid elongase 2 / Q9JLJ4* / Q9NXB9* / Elongation of very long chain fatty acids protein 2 *ENSDARG0000004541430
elovl6 / Q6PC64 / ELOVL fatty acid elongase 6 / Q920L5* / Q9H5J4* / Elongation of very long chain fatty acids protein 6 *ENSDARG0000000440221
elovl6l / ELOVL family member 6, elongation of long chain fatty acids likeENSDARG0000003863918
zgc:92749ENSDARG0000001263218


Protein motifs (from Interpro)
Interpro ID Name
 IPR002076  ELO family
 IPR033681  Elongation of very long chain fatty acids protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IEA
 biological_processGO:0006636 unsaturated fatty acid biosynthetic process IEA
 biological_processGO:0019367 fatty acid elongation, saturated fatty acid IBA
 biological_processGO:0030148 sphingolipid biosynthetic process IBA
 biological_processGO:0034625 fatty acid elongation, monounsaturated fatty acid IBA
 biological_processGO:0034626 fatty acid elongation, polyunsaturated fatty acid IBA
 biological_processGO:0035338 long-chain fatty-acyl-CoA biosynthetic process IEA
 biological_processGO:0042761 very long-chain fatty acid biosynthetic process IEA
 biological_processGO:0048794 swim bladder development IGI
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IBA
 molecular_functionGO:0009922 fatty acid elongase activity IBA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0102336 3-oxo-arachidoyl-CoA synthase activity IEA
 molecular_functionGO:0102337 3-oxo-cerotoyl-CoA synthase activity IEA
 molecular_functionGO:0102338 3-oxo-lignoceronyl-CoA synthase activity IEA
 molecular_functionGO:0102756 very-long-chain 3-ketoacyl-CoA synthase activity IEA


Pathways (from Reactome)
Pathway description
Linoleic acid (LA) metabolism
alpha-linolenic acid (ALA) metabolism
Synthesis of very long-chain fatty acyl-CoAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000076 swim bladder swim bladder uninflated , abnormal
swim bladder decreased distribution , abnormal
swim bladder mesenchyme decreased distribution , abnormal
swim bladder epithelium decreased distribution , abnormal
swim bladder mesothelial cell decreased distribution , abnormal
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 ZFA:0000084 yolk yolk composition , abnormal
Show

 ZFA:0001094 whole organism whole organism anterior-posterior axis increased curvature , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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