ENSG00000066322


Homo sapiens

Features
Gene ID: ENSG00000066322
  
Biological name :ELOVL1
  
Synonyms : ELOVL1 / ELOVL fatty acid elongase 1 / Q9BW60
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p34.2
Gene start: 43363397
Gene end: 43368074
  
Corresponding Affymetrix probe sets: 218028_at (Human Genome U133 Plus 2.0 Array)   57163_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361536
Ensembl peptide - ENSP00000416024
Ensembl peptide - ENSP00000477602
NCBI entrez gene - 64834     See in Manteia.
OMIM - 611813
RefSeq - NM_001256402
RefSeq - NM_001256399
RefSeq - NM_001256401
RefSeq - NM_022821
RefSeq Peptide - NP_001243328
RefSeq Peptide - NP_001243330
RefSeq Peptide - NP_001243331
RefSeq Peptide - NP_073732
swissprot - Q9BW60
Ensembl - ENSG00000066322
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 elovl1aENSDARG00000099960Danio rerio
 elovl1bENSDARG00000103735Danio rerio
 ELOVL1ENSGALG00000009988Gallus gallus
 Elovl1ENSMUSG00000006390Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A1L3X0 / ELOVL7 / ELOVL fatty acid elongase 7ENSG0000016418157
ELOVL4 / Q9GZR5 / ELOVL fatty acid elongase 4ENSG0000011840241
ELOVL5 / Q9NYP7 / ELOVL fatty acid elongase 5ENSG0000001266035
ELOVL2 / Q9NXB9 / ELOVL fatty acid elongase 2ENSG0000019797733
ELOVL6 / Q9H5J4 / ELOVL fatty acid elongase 6ENSG0000017052223
ELOVL3 / Q9HB03 / ELOVL fatty acid elongase 3ENSG0000011991523


Protein motifs (from Interpro)
Interpro ID Name
 IPR002076  ELO family
 IPR030457  ELO family, conserved site
 IPR033681  Elongation of very long chain fatty acids protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IEA
 biological_processGO:0019367 fatty acid elongation, saturated fatty acid IDA
 biological_processGO:0030148 sphingolipid biosynthetic process IMP
 biological_processGO:0034625 fatty acid elongation, monounsaturated fatty acid IDA
 biological_processGO:0034626 fatty acid elongation, polyunsaturated fatty acid IBA
 biological_processGO:0035338 long-chain fatty-acyl-CoA biosynthetic process TAS
 biological_processGO:0036109 alpha-linolenic acid metabolic process TAS
 biological_processGO:0042761 very long-chain fatty acid biosynthetic process IDA
 biological_processGO:0043651 linoleic acid metabolic process TAS
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0009922 fatty acid elongase activity EXP
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0102336 3-oxo-arachidoyl-CoA synthase activity IEA
 molecular_functionGO:0102337 3-oxo-cerotoyl-CoA synthase activity IEA
 molecular_functionGO:0102338 3-oxo-lignoceronyl-CoA synthase activity IEA
 molecular_functionGO:0102756 very-long-chain 3-ketoacyl-CoA synthase activity IEA


Pathways (from Reactome)
Pathway description
Linoleic acid (LA) metabolism
alpha-linolenic acid (ALA) metabolism
Synthesis of very long-chain fatty acyl-CoAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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