ENSG00000197977


Homo sapiens

Features
Gene ID: ENSG00000197977
  
Biological name :ELOVL2
  
Synonyms : ELOVL2 / ELOVL fatty acid elongase 2 / Q9NXB9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p24.2
Gene start: 10980759
Gene end: 11044314
  
Corresponding Affymetrix probe sets: 213712_at (Human Genome U133 Plus 2.0 Array)   220029_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000346693
NCBI entrez gene - 54898     See in Manteia.
OMIM - 611814
RefSeq - XM_011514717
RefSeq - NM_017770
RefSeq - XM_011514716
RefSeq Peptide - NP_060240
swissprot - Q9NXB9
swissprot - A0A024QZV3
Ensembl - ENSG00000197977
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 elovl2ENSDARG00000045414Danio rerio
 ELOVL2ENSGALG00000012748Gallus gallus
 Elovl2ENSMUSG00000021364Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ELOVL5 / Q9NYP7 / ELOVL fatty acid elongase 5ENSG0000001266056
ELOVL4 / Q9GZR5 / ELOVL fatty acid elongase 4ENSG0000011840242
A1L3X0 / ELOVL7 / ELOVL fatty acid elongase 7ENSG0000016418138
ELOVL1 / Q9BW60 / ELOVL fatty acid elongase 1ENSG0000006632231
ELOVL6 / Q9H5J4 / ELOVL fatty acid elongase 6ENSG0000017052221
ELOVL3 / Q9HB03 / ELOVL fatty acid elongase 3ENSG0000011991520


Protein motifs (from Interpro)
Interpro ID Name
 IPR002076  ELO family
 IPR030457  ELO family, conserved site
 IPR033680  Elongation of very long chain fatty acids protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000038 very long-chain fatty acid metabolic process IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IEA
 biological_processGO:0006636 unsaturated fatty acid biosynthetic process IEA
 biological_processGO:0019367 fatty acid elongation, saturated fatty acid IBA
 biological_processGO:0030148 sphingolipid biosynthetic process IBA
 biological_processGO:0034625 fatty acid elongation, monounsaturated fatty acid IBA
 biological_processGO:0034626 fatty acid elongation, polyunsaturated fatty acid IEA
 biological_processGO:0035338 long-chain fatty-acyl-CoA biosynthetic process TAS
 biological_processGO:0036109 alpha-linolenic acid metabolic process TAS
 biological_processGO:0042761 very long-chain fatty acid biosynthetic process IDA
 biological_processGO:0043651 linoleic acid metabolic process TAS
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0009922 fatty acid elongase activity TAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups IEA
 molecular_functionGO:0102336 3-oxo-arachidoyl-CoA synthase activity IEA
 molecular_functionGO:0102337 3-oxo-cerotoyl-CoA synthase activity IEA
 molecular_functionGO:0102338 3-oxo-lignoceronyl-CoA synthase activity IEA
 molecular_functionGO:0102756 very-long-chain 3-ketoacyl-CoA synthase activity IEA


Pathways (from Reactome)
Pathway description
Linoleic acid (LA) metabolism
alpha-linolenic acid (ALA) metabolism
Synthesis of very long-chain fatty acyl-CoAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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