ENSG00000170522


Homo sapiens

Features
Gene ID: ENSG00000170522
  
Biological name :ELOVL6
  
Synonyms : ELOVL6 / ELOVL fatty acid elongase 6 / Q9H5J4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q25
Gene start: 110045846
Gene end: 110199199
  
Corresponding Affymetrix probe sets: 204256_at (Human Genome U133 Plus 2.0 Array)   210868_s_at (Human Genome U133 Plus 2.0 Array)   227491_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000304736
Ensembl peptide - ENSP00000426086
Ensembl peptide - ENSP00000425488
Ensembl peptide - ENSP00000424023
Ensembl peptide - ENSP00000378105
NCBI entrez gene - 79071     See in Manteia.
OMIM - 611546
RefSeq - NM_024090
RefSeq - XM_011532235
RefSeq - XM_011532234
RefSeq - XM_011532233
RefSeq - NM_001130721
RefSeq Peptide - NP_001124193
RefSeq Peptide - NP_076995
swissprot - D6RCU0
swissprot - Q9H5J4
swissprot - A0A024RDK5
swissprot - D6RBP4
swissprot - D6RHI2
Ensembl - ENSG00000170522
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 elovl6ENSDARG00000004402Danio rerio
 ELOVL6ENSGALG00000012131Gallus gallus
 Elovl6ENSMUSG00000041220Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ELOVL3 / Q9HB03 / ELOVL fatty acid elongase 3ENSG0000011991546
A1L3X0 / ELOVL7 / ELOVL fatty acid elongase 7ENSG0000016418126
ELOVL1 / Q9BW60 / ELOVL fatty acid elongase 1ENSG0000006632224
ELOVL4 / Q9GZR5 / ELOVL fatty acid elongase 4ENSG0000011840223
ELOVL2 / Q9NXB9 / ELOVL fatty acid elongase 2ENSG0000019797723
ELOVL5 / Q9NYP7 / ELOVL fatty acid elongase 5ENSG0000001266022


Protein motifs (from Interpro)
Interpro ID Name
 IPR002076  ELO family
 IPR030457  ELO family, conserved site
 IPR033675  Elongation of very long chain fatty acids protein 6


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IEA
 biological_processGO:0006636 unsaturated fatty acid biosynthetic process IEA
 biological_processGO:0019367 fatty acid elongation, saturated fatty acid IEA
 biological_processGO:0030148 sphingolipid biosynthetic process IBA
 biological_processGO:0030497 fatty acid elongation IEA
 biological_processGO:0034625 fatty acid elongation, monounsaturated fatty acid IBA
 biological_processGO:0034626 fatty acid elongation, polyunsaturated fatty acid IBA
 biological_processGO:0035338 long-chain fatty-acyl-CoA biosynthetic process TAS
 biological_processGO:0042759 long-chain fatty acid biosynthetic process IDA
 biological_processGO:0042761 very long-chain fatty acid biosynthetic process IEA
 biological_processGO:0045540 regulation of cholesterol biosynthetic process TAS
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0009922 fatty acid elongase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups IEA
 molecular_functionGO:0102336 3-oxo-arachidoyl-CoA synthase activity IEA
 molecular_functionGO:0102337 3-oxo-cerotoyl-CoA synthase activity IEA
 molecular_functionGO:0102338 3-oxo-lignoceronyl-CoA synthase activity IEA
 molecular_functionGO:0102756 very-long-chain 3-ketoacyl-CoA synthase activity IEA


Pathways (from Reactome)
Pathway description
Activation of gene expression by SREBF (SREBP)
Synthesis of very long-chain fatty acyl-CoAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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