ENSDARG00000100114


Danio rerio

Features
Gene ID: ENSDARG00000100114
  
Biological name :sf3a3
  
Synonyms : sf3a3 / splicing factor 3a, subunit 3
  
Possible biological names infered from orthology : Q12874 / Q9D554
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 17288529
Gene end: 17304995
  
Corresponding Affymetrix probe sets: Dr.25120.2.S1_at (Zebrafish Array)   NM_001004289_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000140243
Ensembl peptide - ENSDARP00000151358
Ensembl peptide - ENSDARP00000140959
Ensembl peptide - ENSDARP00000135753
NCBI entrez gene - 446168     See in Manteia.
RefSeq - NM_001004289
RefSeq Peptide - NP_001004289
swissprot - A0A0R4IZ70
swissprot - A0A0R4ILH7
ZFIN ID - ZDB-GENE-040908-1
Ensembl - ENSDARG00000100114
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SF3A3ENSGALG00000001540Gallus gallus
 SF3A3ENSG00000183431Homo sapiens
 Sf3a3ENSMUSG00000028902Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sde2 / SDE2 telomere maintenance homolog (S. pombe) / Q6IQ49* / Q8K1J5* / SDE2 telomere maintenance homolog* / Replication stress response regulator SDE2 *ENSDARG000000241248


Protein motifs (from Interpro)
Interpro ID Name
 IPR000690  Matrin/U1-C, C2H2-type zinc finger
 IPR021966  Splicing factor SF3a60 binding domain
 IPR024598  Domain of unknown function DUF3449
 IPR031774  SF3A3 domain
 IPR031776  Splicing factor 3A subunit 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome IEA
 biological_processGO:0060218 hematopoietic stem cell differentiation IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005681 spliceosomal complex IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain necrotic , abnormal
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 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0001077 thymus primordium thymus primordium common lymphoid progenitor absent , abnormal
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 ZFA:0001094 whole organism whole organism viability , abnormal
whole organism necrotic , abnormal
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 ZFA:0005028 ventral wall of dorsal aorta ventral wall of dorsal aorta hematopoietic stem cell absent , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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