ENSG00000183431


Homo sapiens

Features
Gene ID: ENSG00000183431
  
Biological name :SF3A3
  
Synonyms : Q12874 / SF3A3 / splicing factor 3a subunit 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p34.3
Gene start: 37956975
Gene end: 37990921
  
Corresponding Affymetrix probe sets: 203818_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000362110
NCBI entrez gene - 10946     See in Manteia.
OMIM - 605596
RefSeq - NM_006802
RefSeq - NM_001320830
RefSeq Peptide - NP_001307759
RefSeq Peptide - NP_006793
swissprot - Q12874
Ensembl - ENSG00000183431
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sf3a3ENSDARG00000100114Danio rerio
 SF3A3ENSGALG00000001540Gallus gallus
 Sf3a3ENSMUSG00000028902Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SDE2 / Q6IQ49 / SDE2 telomere maintenance homologENSG0000014375110


Protein motifs (from Interpro)
Interpro ID Name
 IPR000690  Matrin/U1-C, C2H2-type zinc finger
 IPR021966  Splicing factor SF3a60 binding domain
 IPR024598  Domain of unknown function DUF3449
 IPR031774  SF3A3 domain
 IPR031776  Splicing factor 3A subunit 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000375 RNA splicing, via transesterification reactions TAS
 biological_processGO:0000389 mRNA 3"-splice site recognition TAS
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006397 mRNA processing IMP
 biological_processGO:0008380 RNA splicing TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005681 spliceosomal complex IDA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000099995 SF3A1 / Q15459 / splicing factor 3a subunit 1  / complex
 ENSG00000104897 SF3A2 / Q15428 / splicing factor 3a subunit 2  / complex






 

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