ENSDARG00000100151


Danio rerio

Features
Gene ID: ENSDARG00000100151
  
Biological name :appl2
  
Synonyms : adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 / appl2
  
Possible biological names infered from orthology : G5E8P0 / Q96RT7 / TUBGCP6 / tubulin gamma complex associated protein 6
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 5755314
Gene end: 5791686
  
Corresponding Affymetrix probe sets: Dr.15107.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000131463
Ensembl peptide - ENSDARP00000141315
swissprot - A0A0G2KGM8
swissprot - F1RB27
ZFIN ID - ZDB-GENE-081016-2
Ensembl - ENSDARG00000100151
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TUBGCP6ENSGALG00000032156Gallus gallus
 Q96RT7ENSG00000128159Homo sapiens
 G5E8P0ENSMUSG00000051786Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tubgcp5 / tubulin, gamma complex associated protein 5 / Q8BKN5* / Q96RT8*ENSDARG0000007744210
tubgcp2 / tubulin, gamma complex associated protein 2 / Q921G8* / Q9BSJ2*ENSDARG000000130799
tubgcp3 / tubulin, gamma complex associated protein 3 / P58854* / Q96CW5*ENSDARG000000291339
tubgcp4 / tubulin, gamma complex associated protein 4 / Q9D4F8* / Q9UGJ1*ENSDARG000000053748


Protein motifs (from Interpro)
Interpro ID Name
 IPR007259  Gamma-tubulin complex component protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000226 microtubule cytoskeleton organization IEA
 biological_processGO:0007020 microtubule nucleation IEA
 biological_processGO:0031122 cytoplasmic microtubule organization IBA
 biological_processGO:0051298 centrosome duplication IBA
 biological_processGO:0051321 meiotic cell cycle IBA
 biological_processGO:0051415 microtubule nucleation by interphase microtubule organizing center IBA
 biological_processGO:0090307 mitotic spindle assembly IBA
 cellular_componentGO:0000922 spindle pole IEA
 cellular_componentGO:0000923 equatorial microtubule organizing center IBA
 cellular_componentGO:0005768 endosome IGI
 cellular_componentGO:0005813 centrosome IBA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0008274 gamma-tubulin ring complex IBA
 molecular_functionGO:0005200 structural constituent of cytoskeleton IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043015 gamma-tubulin binding IBA
 molecular_functionGO:0051011 microtubule minus-end binding IBA


Pathways (from Reactome)
Pathway description
Recruitment of mitotic centrosome proteins and complexes
Recruitment of NuMA to mitotic centrosomes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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