ENSDARG00000005374


Danio rerio

Features
Gene ID: ENSDARG00000005374
  
Biological name :tubgcp4
  
Synonyms : tubgcp4 / tubulin, gamma complex associated protein 4
  
Possible biological names infered from orthology : Q9D4F8 / Q9UGJ1
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 52929964
Gene end: 52950123
  
Corresponding Affymetrix probe sets: Dr.11990.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000025789
Ensembl peptide - ENSDARP00000143044
NCBI entrez gene - 557155     See in Manteia.
swissprot - B3DIU9
ZFIN ID - ZDB-GENE-081022-124
Ensembl - ENSDARG00000005374
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TUBGCP4ENSGALG00000008549Gallus gallus
 Q9UGJ1ENSG00000137822Homo sapiens
 Q9D4F8ENSMUSG00000027263Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
appl2 / adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 / Q96RT7* / TUBGCP6* / tubulin gamma complex associated protein 6*ENSDARG0000010015120
tubgcp5 / tubulin, gamma complex associated protein 5 / Q8BKN5* / Q96RT8*ENSDARG0000007744219
tubgcp3 / tubulin, gamma complex associated protein 3 / P58854* / Q96CW5*ENSDARG0000002913317
tubgcp2 / tubulin, gamma complex associated protein 2 / Q921G8* / Q9BSJ2*ENSDARG0000001307915


Protein motifs (from Interpro)
Interpro ID Name
 IPR007259  Gamma-tubulin complex component protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000226 microtubule cytoskeleton organization IEA
 biological_processGO:0007020 microtubule nucleation IEA
 biological_processGO:0031122 cytoplasmic microtubule organization IBA
 biological_processGO:0042670 retinal cone cell differentiation IMP
 biological_processGO:0051298 centrosome duplication IBA
 biological_processGO:0051321 meiotic cell cycle IBA
 biological_processGO:0051415 microtubule nucleation by interphase microtubule organizing center IBA
 biological_processGO:0060221 retinal rod cell differentiation IMP
 biological_processGO:0090307 mitotic spindle assembly IBA
 cellular_componentGO:0000922 spindle pole IEA
 cellular_componentGO:0000923 equatorial microtubule organizing center IBA
 cellular_componentGO:0000930 gamma-tubulin complex IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IBA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton IBA
 molecular_functionGO:0043015 gamma-tubulin binding IBA
 molecular_functionGO:0051011 microtubule minus-end binding IBA


Pathways (from Reactome)
Pathway description
Recruitment of mitotic centrosome proteins and complexes
Recruitment of NuMA to mitotic centrosomes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye decreased diameter , abnormal
eye decreased size , abnormal
Show

 ZFA:0000152 retina retina cell circular , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001115 trunk trunk anatomical axis decreased length , abnormal
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 ZFA:0009262 retinal cone cell retinal cone cell decreased amount , abnormal
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 ZFA:0009275 retinal rod cell retinal rod cell absent , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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