ENSDARG00000101090


Danio rerio

Features
Gene ID: ENSDARG00000101090
  
Biological name :pappaa
  
Synonyms : pappaa / pregnancy-associated plasma protein A, pappalysin 1a
  
Possible biological names infered from orthology : PAPPA / pappalysin 1 / Q13219 / Q8R4K8
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 70345518
Gene end: 70519104
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000134645
NCBI entrez gene - 101448000     See in Manteia.
RefSeq - NM_001278805
RefSeq Peptide - NP_001265734
swissprot - A0A0G2KQH4
ZFIN ID - ZDB-GENE-121113-1
Ensembl - ENSDARG00000101090
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PAPPAENSGALG00000007079Gallus gallus
 PAPPAENSG00000182752Homo sapiens
 PappaENSMUSG00000028370Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pappab / pregnancy-associated plasma protein A, pappalysin 1b / PAPPA* / Q8R4K8* / Q13219* / pappalysin 1*ENSDARG0000005985873
pappa2 / pappalysin 2 / Q9BXP8*ENSDARG0000007602043


Protein motifs (from Interpro)
Interpro ID Name
 IPR000436  Sushi/SCR/CCP domain
 IPR000800  Notch domain
 IPR003961  Fibronectin type III
 IPR006558  LamG-like jellyroll fold
 IPR008754  Peptidase M43, pregnancy-associated plasma-A
 IPR011936  Myxococcus cysteine-rich repeat
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR030433  Pappalysin-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0046959 habituation IMP
 molecular_functionGO:0004222 metalloendopeptidase activity IEA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism decreased life span , abnormal
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 ZFA:0001117 post-vent region post-vent region kinked , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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