ENSDARG00000101332


Danio rerio

Features
Gene ID: ENSDARG00000101332
  
Biological name :uba2
  
Synonyms : Q7SXG4 / uba2 / ubiquitin-like modifier activating enzyme 2
  
Possible biological names infered from orthology : Q9UBT2 / Q9Z1F9
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 12811709
Gene end: 12824939
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000130924
Ensembl peptide - ENSDARP00000139796
Ensembl peptide - ENSDARP00000140060
swissprot - A0A0R4IV65
swissprot - Q7SXG4
ZFIN ID - ZDB-GENE-040426-2681
Ensembl - ENSDARG00000101332
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 UBA2ENSGALG00000005006Gallus gallus
 UBA2ENSG00000126261Homo sapiens
 Uba2ENSMUSG00000052997Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000594  THIF-type NAD/FAD binding fold
 IPR023318  Ubiquitin activating enzyme, alpha domain superfamily
 IPR028077  Ubiquitin/SUMO-activating enzyme ubiquitin-like domain
 IPR030661  SUMO-activating enzyme subunit Uba2
 IPR032426  SUMO-activating enzyme subunit 2, C-terminal domain
 IPR033127  Ubiquitin-activating enzyme E1, Cys active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016925 protein sumoylation ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0031510 SUMO activating enzyme complex ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008641 ubiquitin-like modifier activating enzyme activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016881 acid-amino acid ligase activity IEA
 molecular_functionGO:0019948 SUMO activating enzyme activity IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
SUMO is conjugated to E1 (UBA2:SAE1)
SUMO is transferred from E1 to E2 (UBE2I, UBC9)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000010487 sae1 / Q6IQS6 / SUMO1 activating enzyme subunit 1 / Q9UBE0* / Q9R1T2* / SUMO-activating enzyme subunit 1 SUMO-activating enzyme subunit 1, N-terminally processed*  / complex
 ENSDARG00000044267 sumo1 / Q7SZR5 / small ubiquitin-like modifier 1 / P63166* / P63165* / Small ubiquitin-related modifier 1 *  / complex / reaction
 ENSDARG00000052649 Q9DDJ0 / ube2ia / ubiquitin-conjugating enzyme E2Ia / UBE2I* / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSDARG00000007438 ube2ib / Q9W6H5 / ubiquitin-conjugating enzyme E2Ib / UBE2I* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction






 

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