ENSDARG00000101903


Danio rerio

Features
Gene ID: ENSDARG00000101903
  
Biological name :zfyve9a
  
Synonyms : zfyve9a / zinc finger, FYVE domain containing 9a
  
Possible biological names infered from orthology : O95405 / ZFYVE9 / zinc finger, FYVE domain containing 9 / zinc finger FYVE-type containing 9
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 19280829
Gene end: 19354622
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000156525
Ensembl peptide - ENSDARP00000131596
NCBI entrez gene - 100005449     See in Manteia.
RefSeq - XM_001344468
RefSeq - XM_005171197
swissprot - A5PMI2
ZFIN ID - ZDB-GENE-070705-182
Ensembl - ENSDARG00000101903
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ZFYVE9ENSGALG00000010613Gallus gallus
 O95405ENSG00000157077Homo sapiens
 Zfyve9ENSMUSG00000034557Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
zfyve16 / zinc finger, FYVE domain containing 16 / Q7Z3T8* / Q80U44* / zinc finger FYVE-type containing 16*ENSDARG0000007574737
zfyve9b / zinc finger, FYVE domain containing 9b / ZFYVE9* / O95405* / zinc finger FYVE-type containing 9* / zinc finger, FYVE domain containing 9*ENSDARG0000010076434
pikfyve / phosphoinositide kinase, FYVE finger containing / Q9Y2I7* / Q9Z1T6* / phosphoinositide kinase, FYVE-type zinc finger containing*ENSDARG0000005611213
zfyve28 / zinc finger, FYVE domain containing 28 / Q6ZPK7* / Q9HCC9* / zinc finger FYVE-type containing 28*ENSDARG000000604308
zfyve21 / zinc finger, FYVE domain containing 21 / Q8VCM3* / Q9BQ24* / zinc finger FYVE-type containing 21*ENSDARG000000278875


Protein motifs (from Interpro)
Interpro ID Name
 IPR000306  FYVE zinc finger
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017455  Zinc finger, FYVE-related
 IPR022557  Domain of unknown function DUF3480
 IPR024608  Smad anchor for receptor activation, Smad-binding domain
 IPR035438  Zinc finger FYVE domain containing protein, SARA/endofin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IMP
 biological_processGO:0048699 generation of neurons IMP
 biological_processGO:0072574 hepatocyte proliferation IMP
 cellular_componentGO:0005768 endosome IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
TGF-beta receptor signaling activates SMADs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000075 spinal cord spinal cord generation of neurons process quality , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000042259 tgfbr1b / transforming growth factor, beta receptor 1 b / P36897* / TGFBR1* / transforming growth factor beta receptor 1*  / complex / reaction
 ENSDARG00000017494 tgfbr1a / transforming growth factor, beta receptor 1 a / Q64729* / TGFBR1* / P36897* / transforming growth factor beta receptor 1* / transforming growth factor, beta receptor I*  / complex / reaction
 ENSDARG00000034895 tgfb1b / transforming growth factor, beta 1b / TGFB1* / P04202* / P01137* / transforming growth factor beta 1*  / complex / reaction
 ENSDARG00000036096 smad3a / SMAD family member 3a / SMAD3* / Q8BUN5* / P84022* / SMAD family member 3* / Mothers against decapentaplegic homolog 3 *  / reaction
 ENSDARG00000006389 smad2 / Q9I9P9 / SMAD family member 2 / Q62432* / Q15796* / Mothers against decapentaplegic homolog 2 *  / reaction
 ENSDARG00000034541 tgfbr2b / transforming growth factor beta receptor 2b / Q62312* / TGFBR2* / P37173* / transforming growth factor beta receptor 2* / transforming growth factor, beta receptor II*  / reaction / complex
 ENSDARG00000059363 tgfbr2a / transforming growth factor beta receptor 2a / P37173* / TGFBR2* / transforming growth factor beta receptor 2*  / reaction / complex






 

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