ENSDARG00000102634


Danio rerio

Features
Gene ID: ENSDARG00000102634
  
Biological name :parn
  
Synonyms : parn / poly(A)-specific ribonuclease (deadenylation nuclease)
  
Possible biological names infered from orthology : O95453 / poly(A)-specific ribonuclease
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 59314675
Gene end: 59324539
  
Corresponding Affymetrix probe sets: Dr.2313.1.S1_at (Zebrafish Array)   NM_201088_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000133177
Ensembl peptide - ENSDARP00000140690
Ensembl peptide - ENSDARP00000139642
Ensembl peptide - ENSDARP00000139131
Ensembl peptide - ENSDARP00000137321
NCBI entrez gene - 791461     See in Manteia.
RefSeq - NM_001320404
RefSeq - NM_201088
RefSeq Peptide - NP_001307333
RefSeq Peptide - NP_957382
swissprot - A0A0R4IHL6
swissprot - A0A0R4IYB9
swissprot - A0A0R4IX97
swissprot - A0A0R4IW61
swissprot - A0A0R4IPV8
ZFIN ID - ZDB-GENE-040426-880
Ensembl - ENSDARG00000102634
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PARNENSGALG00000003091Gallus gallus
 PARNENSG00000140694Homo sapiens
 ParnENSMUSG00000022685Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR001374  R3H domain
 IPR006941  Ribonuclease CAF1
 IPR012337  Ribonuclease H-like superfamily
 IPR014789  Poly(A)-specific ribonuclease, RNA-binding
 IPR034042  PARN, R3H domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006402 mRNA catabolic process IEA
 biological_processGO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004535 poly(A)-specific ribonuclease activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Deadenylation of mRNA
KSRP (KHSRP) binds and destabilizes mRNA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009324 myeloid cell myeloid cell decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr