ENSGALG00000003091


Gallus gallus

Features
Gene ID: ENSGALG00000003091
  
Biological name :PARN
  
Synonyms : PARN / poly(A)-specific ribonuclease PARN
  
Possible biological names infered from orthology : O95453 / poly(A)-specific ribonuclease
  
Species: Gallus gallus
  
Chr. number: 14
Strand: -1
Band:
Gene start: 793825
Gene end: 828456
  
Corresponding Affymetrix probe sets: GgaAffx.12665.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004877
NCBI entrez gene - 416423     See in Manteia.
RefSeq - NM_001030629
RefSeq - XM_015294147
RefSeq Peptide - NP_001025800
swissprot - F1NEI8
Ensembl - ENSGALG00000003091
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 parnENSDARG00000102634Danio rerio
 PARNENSG00000140694Homo sapiens
 ParnENSMUSG00000022685Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PNLDC1 / PARN like, ribonuclease domain containing 1 / B2RXZ1* / Q8NA58* / Poly(A)-specific ribonuclease PNLDC1 *ENSGALG0000001162419


Protein motifs (from Interpro)
Interpro ID Name
 IPR001374  R3H domain
 IPR006941  Ribonuclease CAF1
 IPR012337  Ribonuclease H-like superfamily
 IPR012677  Nucleotide-binding alpha-beta plait domain superfamily
 IPR014789  Poly(A)-specific ribonuclease, RNA-binding


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006402 mRNA catabolic process IEA
 biological_processGO:0032212 positive regulation of telomere maintenance via telomerase IEA
 biological_processGO:0051973 positive regulation of telomerase activity IEA
 biological_processGO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic IEA
 biological_processGO:0090669 telomerase RNA stabilization IEA
 biological_processGO:0110008 ncRNA deadenylation IEA
 biological_processGO:1904872 regulation of telomerase RNA localization to Cajal body IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004535 poly(A)-specific ribonuclease activity IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0043169 cation binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Deadenylation of mRNA
KSRP (KHSRP) binds and destabilizes mRNA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000003091 PARN / poly(A)-specific ribonuclease PARN / O95453* / poly(A)-specific ribonuclease*  / complex






 

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