ENSDARG00000103117


Danio rerio

Features
Gene ID: ENSDARG00000103117
  
Biological name :tmprss4a
  
Synonyms : tmprss4a / transmembrane protease, serine 4a
  
Possible biological names infered from orthology : Q8VCA5 / Q9NRS4 / TMPRSS4 / Transmembrane protease serine 4 / transmembrane serine protease 4
  
Species: Danio rerio
  
Chr. number: 15
Strand: 1
Band:
Gene start: 12429206
Gene end: 12459335
  
Corresponding Affymetrix probe sets: Dr.17251.1.A1_at (Zebrafish Array)   NM_001077738_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000130279
Ensembl peptide - ENSDARP00000133846
Ensembl peptide - ENSDARP00000131889
NCBI entrez gene - 777630     See in Manteia.
RefSeq - NM_001077738
RefSeq Peptide - NP_001071206
swissprot - A0A0R4IJV1
swissprot - A0A0R4ID97
swissprot - A0A0R4IB12
ZFIN ID - ZDB-GENE-061103-631
Ensembl - ENSDARG00000103117
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TMPRSS4ENSGALG00000007406Gallus gallus
 Q9NRS4ENSG00000137648Homo sapiens
 Q8VCA5ENSMUSG00000032091Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tmprss4b / transmembrane protease, serine 4b / Q9NRS4* / Q8VCA5* / TMPRSS4* / transmembrane serine protease 4* / Transmembrane protease serine 4 *ENSDARG0000001286046
tmprss2 / transmembrane protease, serine 2 / O15393* / transmembrane serine protease 2*ENSDARG0000009868636
tmprss3a / transmembrane protease, serine 3a / Q8K1T0* / P57727* / TMPRSS3* / transmembrane serine protease 3* / transmembrane protease, serine 3*ENSDARG0000005331533
tmprss5 / transmembrane protease, serine 5 / Q9H3S3* / Q9ER04* / transmembrane serine protease 5* / transmembrane protease, serine 5 (spinesin)*ENSDARG0000008771731
tmprss13b / transmembrane protease, serine 13b / Q9BYE2* / TMPRSS13* / transmembrane serine protease 13*ENSDARG0000007757331
tmprss13a / transmembrane protease, serine 13a / Q9BYE2* / TMPRSS13* / transmembrane serine protease 13*ENSDARG0000010096930
st14a / suppression of tumorigenicity 14 (colon carcinoma) a / ST14* / Q9Y5Y6* / P56677* / suppression of tumorigenicity 14* / suppression of tumorigenicity 14 (colon carcinoma)*ENSDARG0000006117330
st14b / suppression of tumorigenicity 14 (colon carcinoma) b / ST14* / Q9Y5Y6* / P56677* / suppression of tumorigenicity 14* / suppression of tumorigenicity 14 (colon carcinoma)*ENSDARG0000004465530
hpn / hepsin / O35453* / P05981* / Serine protease hepsin Serine protease hepsin non-catalytic chain Serine protease hepsin catalytic chain*ENSDARG0000002760929
zmp:0000001114ENSDARG0000010008828
corin / corin, serine peptidase / Q9Y5Q5* / Q9Z319* / Atrial natriuretic peptide-converting enzyme Atrial natriuretic peptide-converting enzyme, N-terminal propeptide Atrial natriuretic pep...ENSDARG0000010128128
tmprss15 / transmembrane protease, serine 15 / P97435* / P98073* / transmembrane serine protease 15*ENSDARG0000007939326
CR352265.1ENSDARG0000006275826
si:dkey-22n8.2 / Q8K1T0* / P57727* / TMPRSS3* / transmembrane serine protease 3* / transmembrane protease, serine 3*ENSDARG0000003654526
tmprss9 / transmembrane protease, serine 9 / Q7Z410* / transmembrane serine protease 9*ENSDARG0000002984125
zgc:55888ENSDARG0000001653825
CR352265.4 / Q7RTY8* / TMPRSS7* / transmembrane serine protease 7*ENSDARG0000011657516


Protein motifs (from Interpro)
Interpro ID Name
 IPR001190  SRCR domain
 IPR001254  Serine proteases, trypsin domain
 IPR002172  Low-density lipoprotein (LDL) receptor class A repeat
 IPR009003  Peptidase S1, PA clan
 IPR017448  SRCR-like domain
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0005044 scavenger receptor activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000105 epidermis epidermis disorganized , abnormal
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 ZFA:0000548 musculature system musculature system disorganized , abnormal
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 ZFA:0001094 whole organism whole organism structure , abnormal
whole organism decreased size , abnormal
whole organism morphology , abnormal
whole organism viability , abnormal
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 ZFA:0001115 trunk trunk disorganized , abnormal
Show

 ZFA:0001117 post-vent region post-vent region disorganized , abnormal
Show

 ZFA:0005249 vasculature vasculature degenerate , abnormal
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 ZFA:0009114 muscle cell muscle cell myofibril disorganized , abnormal
Show

 ZFA:0009158 keratinocyte keratinocyte detached from whole organism , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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