ENSG00000137648


Homo sapiens

Features
Gene ID: ENSG00000137648
  
Biological name :TMPRSS4
  
Synonyms : Q9NRS4 / TMPRSS4 / transmembrane serine protease 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q23.3
Gene start: 118077012
Gene end: 118121890
  
Corresponding Affymetrix probe sets: 218960_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000430547
Ensembl peptide - ENSP00000429889
Ensembl peptide - ENSP00000431062
Ensembl peptide - ENSP00000478147
Ensembl peptide - ENSP00000477949
Ensembl peptide - ENSP00000435184
Ensembl peptide - ENSP00000416037
Ensembl peptide - ENSP00000428246
Ensembl peptide - ENSP00000428407
Ensembl peptide - ENSP00000428814
Ensembl peptide - ENSP00000429209
Ensembl peptide - ENSP00000429833
NCBI entrez gene - 56649     See in Manteia.
OMIM - 606565
RefSeq - XM_011542904
RefSeq - NM_001083947
RefSeq - NM_001173551
RefSeq - NM_001173552
RefSeq - NM_001290094
RefSeq - NM_001290096
RefSeq - NM_019894
RefSeq - XM_005271613
RefSeq - XM_005271614
RefSeq - XM_005271615
RefSeq - XM_011542901
RefSeq - XM_011542902
RefSeq - XM_011542903
RefSeq Peptide - NP_001167023
RefSeq Peptide - NP_001277023
RefSeq Peptide - NP_001277025
RefSeq Peptide - NP_063947
RefSeq Peptide - NP_001167022
RefSeq Peptide - NP_001077416
swissprot - H0YBM5
swissprot - Q9NRS4
swissprot - A0A087WTU6
swissprot - E7ESG9
swissprot - E5RJR8
swissprot - E5RIH1
swissprot - G3V124
swissprot - H0YAX8
Ensembl - ENSG00000137648
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmprss4aENSDARG00000103117Danio rerio
 tmprss4bENSDARG00000012860Danio rerio
 TMPRSS4ENSGALG00000007406Gallus gallus
 Q8VCA5ENSMUSG00000032091Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O15393 / TMPRSS2 / transmembrane serine protease 2ENSG0000018401235
Q9BYE2 / TMPRSS13 / transmembrane serine protease 13ENSG0000013774733
P57727 / TMPRSS3 / transmembrane serine protease 3ENSG0000016018332
CORIN / Q9Y5Q5 / corin, serine peptidaseENSG0000014524429
P98073 / TMPRSS15 / transmembrane serine protease 15ENSG0000015464629
Q9H3S3 / TMPRSS5 / transmembrane serine protease 5ENSG0000016668229
HPN / hepsin / P05981ENSG0000010570728
KLKB1 / P03952 / kallikrein B1ENSG0000016434428
Q8IU80 / TMPRSS6 / transmembrane serine protease 6ENSG0000018704528
ST14 / Q9Y5Y6 / suppression of tumorigenicity 14ENSG0000014941828
F11 / P03951 / coagulation factor XIENSG0000008892627
Q7RTY8 / TMPRSS7 / transmembrane serine protease 7ENSG0000017604025
Q7Z410 / TMPRSS9 / transmembrane serine protease 9ENSG0000017829723


Protein motifs (from Interpro)
Interpro ID Name
 IPR001190  SRCR domain
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR002172  Low-density lipoprotein (LDL) receptor class A repeat
 IPR009003  Peptidase S1, PA clan
 IPR017448  SRCR-like domain
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site
 IPR036055  LDL receptor-like superfamily
 IPR036772  SRCR-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0005044 scavenger receptor activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr