ENSG00000166682


Homo sapiens

Features
Gene ID: ENSG00000166682
  
Biological name :TMPRSS5
  
Synonyms : Q9H3S3 / TMPRSS5 / transmembrane serine protease 5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q23.2
Gene start: 113687546
Gene end: 113706373
  
Corresponding Affymetrix probe sets: 221032_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000495454
Ensembl peptide - ENSP00000445930
Ensembl peptide - ENSP00000496410
Ensembl peptide - ENSP00000299882
Ensembl peptide - ENSP00000437761
Ensembl peptide - ENSP00000437937
Ensembl peptide - ENSP00000440783
Ensembl peptide - ENSP00000440976
Ensembl peptide - ENSP00000441104
Ensembl peptide - ENSP00000443681
Ensembl peptide - ENSP00000445502
Ensembl peptide - ENSP00000445528
NCBI entrez gene - 80975     See in Manteia.
OMIM - 606751
RefSeq - XM_017018367
RefSeq - NM_001288749
RefSeq - NM_001288750
RefSeq - NM_001288751
RefSeq - NM_001288752
RefSeq - NM_030770
RefSeq - XM_017018366
RefSeq Peptide - NP_001275680
RefSeq Peptide - NP_001275681
RefSeq Peptide - NP_001275678
RefSeq Peptide - NP_001275679
RefSeq Peptide - NP_110397
swissprot - F5GXT6
swissprot - F5GYA3
swissprot - F5H0U3
swissprot - F5H2M3
swissprot - G5EA43
swissprot - F5H8D2
swissprot - G5EA47
swissprot - Q9H3S3
swissprot - A0A0G2JKU3
swissprot - F5GX83
Ensembl - ENSG00000166682
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmprss5ENSDARG00000087717Danio rerio
 Q9ER04ENSMUSG00000032268Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P57727 / TMPRSS3 / transmembrane serine protease 3ENSG0000016018332
Q9BYE2 / TMPRSS13 / transmembrane serine protease 13ENSG0000013774731
Q8IU80 / TMPRSS6 / transmembrane serine protease 6ENSG0000018704531
O15393 / TMPRSS2 / transmembrane serine protease 2ENSG0000018401231
Q7Z410 / TMPRSS9 / transmembrane serine protease 9ENSG0000017829730
HPN / hepsin / P05981ENSG0000010570729
KLKB1 / P03952 / kallikrein B1ENSG0000016434428
Q9NRS4 / TMPRSS4 / transmembrane serine protease 4ENSG0000013764828
CORIN / Q9Y5Q5 / corin, serine peptidaseENSG0000014524428
Q7RTY8 / TMPRSS7 / transmembrane serine protease 7ENSG0000017604028
ST14 / Q9Y5Y6 / suppression of tumorigenicity 14ENSG0000014941826
P98073 / TMPRSS15 / transmembrane serine protease 15ENSG0000015464626
F11 / P03951 / coagulation factor XIENSG0000008892626


Protein motifs (from Interpro)
Interpro ID Name
 IPR001190  SRCR domain
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR017448  SRCR-like domain
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site
 IPR036772  SRCR-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0005044 scavenger receptor activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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