ENSDARG00000103606


Danio rerio

Features
Gene ID: ENSDARG00000103606
  
Biological name :si:ch211-151g22.1
  
Synonyms : ndst1b / si:ch211-151g22.1
  
Possible biological names infered from orthology : Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 Heparan sulfate N-deacetylase 1 Heparan sulfate N-sulfotransferase 1 / N-deacetylase and N-sulfotransferase 1 / NDST1 / P52848 / Q3UHN9
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 33249478
Gene end: 33447610
  
Corresponding Affymetrix probe sets: Dr.14258.1.S1_at (Zebrafish Array)   Dr.21944.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000137017
Ensembl peptide - ENSDARP00000137411
NCBI entrez gene - 570459     See in Manteia.
RefSeq - NM_001324455
RefSeq - XM_009295591
RefSeq - XM_017352818
RefSeq Peptide - NP_001311384
swissprot - A0A0R4IR84
swissprot - A0A0R4IP80
ZFIN ID - ZDB-GENE-030131-8022
ZFIN ID - ZDB-GENE-091204-12
Ensembl - ENSDARG00000103606
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NDST1ENSGALG00000004581Gallus gallus
 NDST1ENSG00000070614Homo sapiens
 Ndst1ENSMUSG00000054008Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ndst1a / N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1a / NDST1* / Q3UHN9* / P52848* / N-deacetylase and N-sulfotransferase 1* / Bifunctional heparan sulfate N-deacetylase/N-sul...ENSDARG0000006239775
ndst3 / N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 / NDST4* / Q9H3R1* / O95803* / Q9EQH7* / Q9EQW8* / N-deacetylase and N-sulfotransferase 4* / N-deacetylase and N-sulfotrans...ENSDARG0000004177669
ndst2b / N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2b / NDST2* / P52850* / P52849* / AC022400.6* / N-deacetylase and N-sulfotransferase 2* / N-deacetylase/N-sulfotransferase (...ENSDARG0000006067868
ndst2a / N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2a / NDST2* / P52850* / P52849* / AC022400.6* / N-deacetylase and N-sulfotransferase 2* / N-deacetylase/N-sulfotransferase (...ENSDARG0000008626962
hs3st3l / heparan sulfate (glucosamine) 3-O-sulfotransferase 3-likeENSDARG0000005990311
hs3st3b1b / heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1b / Q9Y663* / Q8BKN6* / Q9QZS6* / Q9Y662* / HS3ST3B1* / HS3ST3A1* / heparan sulfate-glucosamine 3-sulfotransferase 3A1* / h...ENSDARG0000008664511
si:ch211-216b21.2 / Q9Y663* / Q8BKN6* / Q9QZS6* / Q9Y662* / HS3ST3B1* / HS3ST3A1* / heparan sulfate-glucosamine 3-sulfotransferase 3A1* / heparan sulfate-glucosamine 3-sulfotransferase 3B1*...ENSDARG0000006025311
hs3st4 / heparan sulfate (glucosamine) 3-O-sulfotransferase 4 / Q9Y661* / heparan sulfate-glucosamine 3-sulfotransferase 4*ENSDARG0000005264811
si:dkey-121b10.7 / HS3ST6* / Q5GFD5* / Q96QI5* / heparan sulfate-glucosamine 3-sulfotransferase 6* / Heparan sulfate glucosamine 3-O-sulfotransferase 6 *ENSDARG0000005994810
hs3st3b1a / heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1a / Q9Y663* / Q9Y662* / HS3ST3B1* / HS3ST3A1* / heparan sulfate-glucosamine 3-sulfotransferase 3B1* / heparan sulfate-gluco...ENSDARG0000009914910
hs3st2 / heparan sulfate (glucosamine) 3-O-sulfotransferase 2 / Q673U1* / Q9Y278* / heparan sulfate-glucosamine 3-sulfotransferase 2*ENSDARG0000005961610
hs3st1l2 / heparan sulfate (glucosamine) 3-O-sulfotransferase 1-like 2 / O35310* / HS3ST1* / O14792* / heparan sulfate-glucosamine 3-sulfotransferase 1* / Heparan sulfate glucosamine 3-O-su...ENSDARG000000355789


Protein motifs (from Interpro)
Interpro ID Name
 IPR000863  Sulfotransferase domain
 IPR021930  Heparan sulphate-N-deacetylase
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0008146 sulfotransferase activity IEA
 molecular_functionGO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
HS-GAG biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000014 dorsal aorta dorsal aorta malformed , abnormal
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 ZFA:0000180 caudal vein caudal vein malformed , abnormal
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 ZFA:0001117 post-vent region post-vent region malformed , abnormal
post-vent region intersegmental vessel decreased mass density , abnormal
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 ZFA:0001285 intersegmental vessel intersegmental vessel decreased amount , abnormal
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 ZFA:0001286 caudal vein plexus caudal vein plexus increased accumulation blood , abnormal
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 ZFA:0005314 blood vessel blood vessel decreased width , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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