ENSDARG00000114670


Danio rerio

Features
Gene ID: ENSDARG00000114670
  
Biological name :ube2c
  
Synonyms : ube2c / ubiquitin-conjugating enzyme E2C
  
Possible biological names infered from orthology : O00762 / Q9D1C1
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 55287823
Gene end: 55297274
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000146732
NCBI entrez gene - 566441     See in Manteia.
RefSeq - NM_001037691
RefSeq Peptide - NP_001032780
swissprot - Q3B745
ZFIN ID - ZDB-GENE-051030-48
Ensembl - ENSDARG00000114670
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 UBE2CENSGALG00000026380Gallus gallus
 UBE2CENSG00000175063Homo sapiens
 Ube2cENSMUSG00000001403Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
flj11011l / hypothetical protein FLJ11011-like (H. sapiens) / Ube2w* / ubiquitin-conjugating enzyme E2W (putative)*ENSDARG0000004536029
ube2w / Q4VBH4 / ubiquitin-conjugating enzyme E2W (putative) / AC022826.2*ENSDARG0000004492329


Protein motifs (from Interpro)
Interpro ID Name
 IPR000608  Ubiquitin-conjugating enzyme E2
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like
 IPR023313  Ubiquitin-conjugating enzyme, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
CDK-mediated phosphorylation and removal of Cdc6
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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