ENSGALG00000026380


Gallus gallus

Features
Gene ID: ENSGALG00000026380
  
Biological name :UBE2C
  
Synonyms : UBE2C / ubiquitin conjugating enzyme E2 C
  
Possible biological names infered from orthology : O00762 / Q9D1C1
  
Species: Gallus gallus
  
Chr. number: 20
Strand: 1
Band:
Gene start: 10709438
Gene end: 10710435
  
Corresponding Affymetrix probe sets: Gga.1245.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000042469
Ensembl peptide - ENSGALP00000061941
NCBI entrez gene - 100859413     See in Manteia.
RefSeq - XM_015296578
swissprot - A0A1L1RT01
swissprot - R4GJY8
Ensembl - ENSGALG00000026380
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ube2cENSDARG00000114670Danio rerio
 UBE2CENSG00000175063Homo sapiens
 Ube2cENSMUSG00000001403Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
UBE2W / AC022826.2* / ubiquitin-conjugating enzyme E2W (putative)*ENSGALG0000004009729


Protein motifs (from Interpro)
Interpro ID Name
 IPR000608  Ubiquitin-conjugating enzyme E2
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like
 IPR023313  Ubiquitin-conjugating enzyme, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IBA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0010458 exit from mitosis IEA
 biological_processGO:0010994 free ubiquitin chain polymerization IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030071 regulation of mitotic metaphase/anaphase transition IBA
 biological_processGO:0031145 anaphase-promoting complex-dependent catabolic process IEA
 biological_processGO:0031536 positive regulation of exit from mitosis IEA
 biological_processGO:0070936 protein K48-linked ubiquitination IEA
 biological_processGO:0070979 protein K11-linked ubiquitination IEA
 cellular_componentGO:0000151 ubiquitin ligase complex IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005680 anaphase-promoting complex IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IBA
 molecular_functionGO:0044389 ubiquitin-like protein ligase binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA
 molecular_functionGO:0061631 ubiquitin conjugating enzyme activity IEA


Pathways (from Reactome)
Pathway description
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
CDK-mediated phosphorylation and removal of Cdc6
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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