ENSDARG00000116835


Danio rerio

Features
Gene ID: ENSDARG00000116835
  
Biological name :park7
  
Synonyms : park7 / parkinson protein 7 / Q5XJ36
  
Possible biological names infered from orthology : Parkinsonism associated deglycase / Protein/nucleic acid deglycase DJ-1 / Q99497 / Q99LX0
  
Species: Danio rerio
  
Chr. number: 11
Strand: 1
Band:
Gene start: 41459408
Gene end: 41475995
  
Corresponding Affymetrix probe sets: Dr.15530.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000150435
NCBI entrez gene - 449674     See in Manteia.
swissprot - Q5XJ36
ZFIN ID - ZDB-GENE-041010-5
Ensembl - ENSDARG00000116835
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PARK7ENSGALG00000036214Gallus gallus
 PARK7ENSG00000116288Homo sapiens
 Park7ENSMUSG00000028964Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002818  DJ-1/PfpI
 IPR006287  Protein/nucleic acid deglycase DJ-1
 IPR029062  Class I glutamine amidotransferase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair ISS
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006517 protein deglycosylation ISS
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0006979 response to oxidative stress IMP
 biological_processGO:0007338 single fertilization IEA
 biological_processGO:0030073 insulin secretion ISS
 biological_processGO:0034599 cellular response to oxidative stress ISS
 biological_processGO:0042593 glucose homeostasis ISS
 biological_processGO:0043523 regulation of neuron apoptotic process ISS
 biological_processGO:0050821 protein stabilization ISS
 biological_processGO:0060548 negative regulation of cell death ISS
 biological_processGO:0070301 cellular response to hydrogen peroxide ISS
 biological_processGO:0106044 guanine deglycation ISS
 biological_processGO:0106045 guanine deglycation, methylglyoxal removal ISS
 biological_processGO:0106046 guanine deglycation, glyoxal removal ISS
 biological_processGO:1903427 negative regulation of reactive oxygen species biosynthetic process ISS
 biological_processGO:2000277 positive regulation of oxidative phosphorylation uncoupler activity ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005739 mitochondrion ISS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0045121 membrane raft IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding ISS
 molecular_functionGO:0008233 peptidase activity ISS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity ISS


Pathways (from Reactome)
Pathway description
SUMOylation of transcription cofactors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001117 post-vent region post-vent region apoptotic , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000052649 Q9DDJ0 / ube2ia / ubiquitin-conjugating enzyme E2Ia / UBE2I* / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSDARG00000044267 sumo1 / Q7SZR5 / small ubiquitin-like modifier 1 / P63166* / P63165* / Small ubiquitin-related modifier 1 *  / reaction / complex
 ENSDARG00000007438 ube2ib / Q9W6H5 / ubiquitin-conjugating enzyme E2Ib / UBE2I* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction






 

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