ENSG00000004846


Homo sapiens

Features
Gene ID: ENSG00000004846
  
Biological name :ABCB5
  
Synonyms : ABCB5 / ATP binding cassette subfamily B member 5 / Q2M3G0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: p21.1
Gene start: 20615207
Gene end: 20777038
  
Corresponding Affymetrix probe sets: 1555371_at (Human Genome U133 Plus 2.0 Array)   1569072_s_at (Human Genome U133 Plus 2.0 Array)   240717_at (Human Genome U133 Plus 2.0 Array)   243167_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000258738
Ensembl peptide - ENSP00000384881
Ensembl peptide - ENSP00000398692
Ensembl peptide - ENSP00000406730
Ensembl peptide - ENSP00000383899
NCBI entrez gene - 340273     See in Manteia.
OMIM - 611785
RefSeq - XM_011515367
RefSeq - NM_001163941
RefSeq - NM_001163942
RefSeq - NM_001163993
RefSeq - NM_178559
RefSeq Peptide - NP_001157465
RefSeq Peptide - NP_848654
RefSeq Peptide - NP_001157414
RefSeq Peptide - NP_001157413
swissprot - H7C165
swissprot - A0A024RA03
swissprot - Q2M3G0
Ensembl - ENSG00000004846
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Abcb5ENSMUSG00000072791Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ABCB1 / P08183 / ATP binding cassette subfamily B member 1ENSG0000008556355
ABCB4 / P21439 / ATP binding cassette subfamily B member 4ENSG0000000547154
ABCB11 / O95342 / ATP binding cassette subfamily B member 11ENSG0000007373446


Protein motifs (from Interpro)
Interpro ID Name
 IPR003439  ABC transporter-like
 IPR003593  AAA+ ATPase domain
 IPR011527  ABC transporter type 1, transmembrane domain
 IPR017871  ABC transporter, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036640  ABC transporter type 1, transmembrane domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006855 drug transmembrane transport IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0042391 regulation of membrane potential IDA
 biological_processGO:0042908 xenobiotic transport IEA
 biological_processGO:0048058 compound eye corneal lens development ISS
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008559 xenobiotic transmembrane transporting ATPase activity TAS
 molecular_functionGO:0015562 efflux transmembrane transporter activity IDA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IEA


Pathways (from Reactome)
Pathway description
ABC-family proteins mediated transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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