ENSG00000005469


Homo sapiens

Features
Gene ID: ENSG00000005469
  
Biological name :CROT
  
Synonyms : carnitine O-octanoyltransferase / CROT / Q9UKG9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q21.12
Gene start: 87345681
Gene end: 87399795
  
Corresponding Affymetrix probe sets: 204573_at (Human Genome U133 Plus 2.0 Array)   231102_at (Human Genome U133 Plus 2.0 Array)   243283_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000413575
Ensembl peptide - ENSP00000331981
Ensembl peptide - ENSP00000404867
Ensembl peptide - ENSP00000411983
NCBI entrez gene - 54677     See in Manteia.
OMIM - 606090
RefSeq - XM_017012370
RefSeq - NM_001143935
RefSeq - NM_001243745
RefSeq - NM_021151
RefSeq - XM_011516337
RefSeq Peptide - NP_001230674
RefSeq Peptide - NP_066974
RefSeq Peptide - NP_001137407
swissprot - Q9UKG9
swissprot - C9J3D7
Ensembl - ENSG00000005469
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 crotENSDARG00000040352Danio rerio
 CROTENSGALG00000008813Gallus gallus
 CrotENSMUSG00000003623Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CRAT / P43155 / carnitine O-acetyltransferaseENSG0000009532130
CPT1A / P50416 / carnitine palmitoyltransferase 1AENSG0000011009028
CPT1C / Q8TCG5 / carnitine palmitoyltransferase 1CENSG0000016916927
CPT1B / Q92523 / carnitine palmitoyltransferase 1BENSG0000020556027
CHAT / P28329 / choline O-acetyltransferaseENSG0000007074827


Protein motifs (from Interpro)
Interpro ID Name
 IPR000542  Acyltransferase ChoActase/COT/CPT


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006091 generation of precursor metabolites and energy IDA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IMP
 biological_processGO:0006635 fatty acid beta-oxidation IEA
 biological_processGO:0009437 carnitine metabolic process ISS
 biological_processGO:0015908 fatty acid transport IEA
 biological_processGO:0015936 coenzyme A metabolic process ISS
 biological_processGO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase TAS
 biological_processGO:0051791 medium-chain fatty acid metabolic process IDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005777 peroxisome NAS
 cellular_componentGO:0005782 peroxisomal matrix TAS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0008458 carnitine O-octanoyltransferase activity TAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA


Pathways (from Reactome)
Pathway description
Beta-oxidation of pristanoyl-CoA
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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