ENSG00000095321


Homo sapiens

Features
Gene ID: ENSG00000095321
  
Biological name :CRAT
  
Synonyms : carnitine O-acetyltransferase / CRAT / P43155
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q34.11
Gene start: 129094810
Gene end: 129111189
  
Corresponding Affymetrix probe sets: 205843_x_at (Human Genome U133 Plus 2.0 Array)   209522_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000395458
Ensembl peptide - ENSP00000394420
Ensembl peptide - ENSP00000400367
Ensembl peptide - ENSP00000404405
Ensembl peptide - ENSP00000315013
Ensembl peptide - ENSP00000377045
Ensembl peptide - ENSP00000390571
NCBI entrez gene - 1384     See in Manteia.
OMIM - 600184
RefSeq - XM_017014275
RefSeq - NM_000755
RefSeq - NM_001257363
RefSeq - XM_005251708
RefSeq - XM_017014274
RefSeq Peptide - NP_000746
RefSeq Peptide - NP_001244292
swissprot - B7ZBP5
swissprot - F2Z2C5
swissprot - H0Y4Z7
swissprot - P43155
swissprot - H7C0E1
swissprot - A6PVN3
Ensembl - ENSG00000095321
  
Related genetic diseases (OMIM): 617917 - ?Neurodegeneration with brain iron accumulation 8, 617917
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 crataENSDARG00000040248Danio rerio
 zgc:154046ENSDARG00000016545Danio rerio
 ENSGALG00000037443Gallus gallus
 CratENSMUSG00000026853Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CHAT / P28329 / choline O-acetyltransferaseENSG0000007074842
CROT / Q9UKG9 / carnitine O-octanoyltransferaseENSG0000000546931
CPT1B / Q92523 / carnitine palmitoyltransferase 1BENSG0000020556031
CPT1A / P50416 / carnitine palmitoyltransferase 1AENSG0000011009031
CPT1C / Q8TCG5 / carnitine palmitoyltransferase 1CENSG0000016916930


Protein motifs (from Interpro)
Interpro ID Name
 IPR000542  Acyltransferase ChoActase/COT/CPT


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0019254 carnitine metabolic process, CoA-linked IDA
 biological_processGO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase TAS
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0005777 peroxisome IEA
 cellular_componentGO:0005782 peroxisomal matrix TAS
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004092 carnitine O-acetyltransferase activity TAS
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA


Pathways (from Reactome)
Pathway description
Beta-oxidation of pristanoyl-CoA
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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