ENSG00000006128


Homo sapiens

Features
Gene ID: ENSG00000006128
  
Biological name :TAC1
  
Synonyms : P20366 / TAC1 / tachykinin precursor 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q21.3
Gene start: 97731908
Gene end: 97740472
  
Corresponding Affymetrix probe sets: 206552_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000289574
Ensembl peptide - ENSP00000289576
Ensembl peptide - ENSP00000321106
NCBI entrez gene - 6863     See in Manteia.
OMIM - 162320
RefSeq - NM_013997
RefSeq - NM_003182
RefSeq - NM_013996
RefSeq - NM_013998
RefSeq Peptide - NP_003173
RefSeq Peptide - NP_054702
RefSeq Peptide - NP_054703
RefSeq Peptide - NP_054704
swissprot - P20366
Ensembl - ENSG00000006128
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tac1ENSDARG00000014490Danio rerio
 TAC1ENSGALG00000009737Gallus gallus
 Tac1ENSMUSG00000061762Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008215  Tachykinin domain
 IPR008216  Tachykinin family
 IPR013055  Tachykinin/Neurokinin-like, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002675 positive regulation of acute inflammatory response IEA
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IDA
 biological_processGO:0007217 tachykinin receptor signaling pathway IBA
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0007268 chemical synaptic transmission IEA
 biological_processGO:0007320 insemination TAS
 biological_processGO:0007616 long-term memory IEA
 biological_processGO:0008217 regulation of blood pressure IEA
 biological_processGO:0008306 associative learning IEA
 biological_processGO:0009582 detection of abiotic stimulus TAS
 biological_processGO:0009725 response to hormone IEA
 biological_processGO:0010459 negative regulation of heart rate IEA
 biological_processGO:0010634 positive regulation of epithelial cell migration IEA
 biological_processGO:0019233 sensory perception of pain IEA
 biological_processGO:0032224 positive regulation of synaptic transmission, cholinergic IEA
 biological_processGO:0032230 positive regulation of synaptic transmission, GABAergic IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0035815 positive regulation of renal sodium excretion IEA
 biological_processGO:0043278 response to morphine IEA
 biological_processGO:0045760 positive regulation of action potential IEA
 biological_processGO:0045778 positive regulation of ossification IEA
 biological_processGO:0046878 positive regulation of saliva secretion IEA
 biological_processGO:0048265 response to pain IEA
 biological_processGO:0050671 positive regulation of lymphocyte proliferation IEA
 biological_processGO:0051496 positive regulation of stress fiber assembly IEA
 biological_processGO:1990090 cellular response to nerve growth factor stimulus IEA
 biological_processGO:2000854 positive regulation of corticosterone secretion IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0005102 signaling receptor binding IBA
 molecular_functionGO:0031835 substance P receptor binding IEA


Pathways (from Reactome)
Pathway description
Tachykinin receptors bind tachykinins
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000115353 TACR1 / P25103 / tachykinin receptor 1  / reaction / complex
 ENSG00000075073 TACR2 / P21452 / tachykinin receptor 2  / complex / reaction






 

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