ENSG00000006534


Homo sapiens

Features
Gene ID: ENSG00000006534
  
Biological name :ALDH3B1
  
Synonyms : aldehyde dehydrogenase 3 family member B1 / ALDH3B1 / P43353
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q13.2
Gene start: 68008578
Gene end: 68029282
  
Corresponding Affymetrix probe sets: 1565731_at (Human Genome U133 Plus 2.0 Array)   205640_at (Human Genome U133 Plus 2.0 Array)   211004_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000473990
Ensembl peptide - ENSP00000484901
Ensembl peptide - ENSP00000483988
Ensembl peptide - ENSP00000481604
Ensembl peptide - ENSP00000479948
Ensembl peptide - ENSP00000478632
Ensembl peptide - ENSP00000478486
Ensembl peptide - ENSP00000478380
Ensembl peptide - ENSP00000477789
NCBI entrez gene - 221     See in Manteia.
OMIM - 600466
RefSeq - NM_001290059
RefSeq - NM_001290058
RefSeq - NM_000694
RefSeq - NM_001030010
RefSeq - NM_001161473
RefSeq Peptide - NP_001276988
RefSeq Peptide - NP_000685
RefSeq Peptide - NP_001025181
RefSeq Peptide - NP_001154945
RefSeq Peptide - NP_001276987
swissprot - Q9BUJ8
swissprot - A0A087X192
swissprot - A0A087WUF8
swissprot - A0A087WU54
swissprot - A0A087WTE0
swissprot - A0A024R5K0
swissprot - A0A024R5D8
swissprot - P43353
swissprot - A0A087X2D4
Ensembl - ENSG00000006534
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aldh3b1ENSDARG00000013839Danio rerio
 ENSGALG00000036044Gallus gallus
 Q80VQ0ENSMUSG00000024885Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P48448 / ALDH3B2 / aldehyde dehydrogenase 3 family member B2ENSG0000013274668
P51648 / ALDH3A2 / aldehyde dehydrogenase 3 family member A2ENSG0000007221053
P30838 / ALDH3A1 / aldehyde dehydrogenase 3 family member A1ENSG0000010860252


Protein motifs (from Interpro)
Interpro ID Name
 IPR012394  Aldehyde dehydrogenase NAD(P)-dependent
 IPR015590  Aldehyde dehydrogenase domain
 IPR016160  Aldehyde dehydrogenase, cysteine active site
 IPR016161  Aldehyde/histidinol dehydrogenase
 IPR016162  Aldehyde dehydrogenase, N-terminal
 IPR029510  Aldehyde dehydrogenase, glutamic acid active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006066 alcohol metabolic process TAS
 biological_processGO:0006068 ethanol catabolic process IEA
 biological_processGO:0006081 cellular aldehyde metabolic process IEA
 biological_processGO:0006629 lipid metabolic process TAS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0030148 sphingolipid biosynthetic process TAS
 biological_processGO:0034599 cellular response to oxidative stress IDA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0046185 aldehyde catabolic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030667 secretory granule membrane TAS
 cellular_componentGO:0031982 vesicle HDA
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004028 3-chloroallyl aldehyde dehydrogenase activity TAS
 molecular_functionGO:0004029 aldehyde dehydrogenase (NAD) activity IEA
 molecular_functionGO:0004030 aldehyde dehydrogenase [NAD(P)+] activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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