ENSG00000108602


Homo sapiens

Features
Gene ID: ENSG00000108602
  
Biological name :ALDH3A1
  
Synonyms : aldehyde dehydrogenase 3 family member A1 / ALDH3A1 / P30838
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p11.2
Gene start: 19737984
Gene end: 19748943
  
Corresponding Affymetrix probe sets: 205623_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000434685
Ensembl peptide - ENSP00000411821
Ensembl peptide - ENSP00000458841
Ensembl peptide - ENSP00000461189
Ensembl peptide - ENSP00000460792
Ensembl peptide - ENSP00000460482
Ensembl peptide - ENSP00000225740
Ensembl peptide - ENSP00000378923
Ensembl peptide - ENSP00000388369
Ensembl peptide - ENSP00000388469
Ensembl peptide - ENSP00000389766
NCBI entrez gene - 218     See in Manteia.
OMIM - 100660
RefSeq - XM_011523731
RefSeq - NM_000691
RefSeq - NM_001135167
RefSeq - NM_001135168
RefSeq - NM_001330150
RefSeq - XM_005256522
RefSeq - XM_005256523
RefSeq - XM_005256524
RefSeq - XM_011523730
RefSeq Peptide - NP_001317079
RefSeq Peptide - NP_000682
RefSeq Peptide - NP_001128639
RefSeq Peptide - NP_001128640
swissprot - I3L4E5
swissprot - E9PNN6
swissprot - C9JMC5
swissprot - C9JKT2
swissprot - I3L1H6
swissprot - I3L3I9
swissprot - P30838
swissprot - A8MYB8
swissprot - I3L3W9
Ensembl - ENSG00000108602
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aldh3a1ENSDARG00000074791Danio rerio
 aldh3a2aENSDARG00000028259Danio rerio
 aldh3a2bENSDARG00000029381Danio rerio
 ALDH3A2ENSGALG00000004763Gallus gallus
 P47739ENSMUSG00000019102Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P51648 / ALDH3A2 / aldehyde dehydrogenase 3 family member A2ENSG0000007221066
P43353 / ALDH3B1 / aldehyde dehydrogenase 3 family member B1ENSG0000000653453
P48448 / ALDH3B2 / aldehyde dehydrogenase 3 family member B2ENSG0000013274642


Protein motifs (from Interpro)
Interpro ID Name
 IPR012394  Aldehyde dehydrogenase NAD(P)-dependent
 IPR015590  Aldehyde dehydrogenase domain
 IPR016160  Aldehyde dehydrogenase, cysteine active site
 IPR016161  Aldehyde/histidinol dehydrogenase
 IPR016162  Aldehyde dehydrogenase, N-terminal
 IPR029510  Aldehyde dehydrogenase, glutamic acid active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006081 cellular aldehyde metabolic process IDA
 biological_processGO:0006805 xenobiotic metabolic process TAS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IDA
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004028 3-chloroallyl aldehyde dehydrogenase activity IEA
 molecular_functionGO:0004029 aldehyde dehydrogenase (NAD) activity IDA
 molecular_functionGO:0004030 aldehyde dehydrogenase [NAD(P)+] activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008106 alcohol dehydrogenase (NADP+) activity IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0018479 benzaldehyde dehydrogenase (NAD+) activity IDA


Pathways (from Reactome)
Pathway description
Phase I - Functionalization of compounds


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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