ENSMUSG00000019102


Mus musculus

Features
Gene ID: ENSMUSG00000019102
  
Biological name :Aldh3a1
  
Synonyms : Aldh3a1 / Mus musculus aldehyde dehydrogenase family 3, subfamily A1 (Aldh3a1), transcript variant 3, mRNA. / P47739
  
Possible biological names infered from orthology : aldehyde dehydrogenase 3 family member A1 / P30838
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B2
Gene start: 61207537
Gene end: 61218421
  
Corresponding Affymetrix probe sets: 10376765 (MoGene1.0st)   1418752_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000019246
Ensembl peptide - ENSMUSP00000104356
Ensembl peptide - ENSMUSP00000118613
NCBI entrez gene - 11670     See in Manteia.
MGI - MGI:1353451
RefSeq - XM_017314226
RefSeq - NM_001112725
RefSeq - NM_001331112
RefSeq - NM_007436
RefSeq - XM_006532023
RefSeq - XM_006532024
RefSeq - XM_006532026
RefSeq - XM_006532027
RefSeq Peptide - NP_001106196
RefSeq Peptide - NP_001318041
RefSeq Peptide - NP_031462
swissprot - B1ATI6
swissprot - P47739
Ensembl - ENSMUSG00000019102
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aldh3a1ENSDARG00000074791Danio rerio
 aldh3a2aENSDARG00000028259Danio rerio
 aldh3a2bENSDARG00000029381Danio rerio
 ALDH3A2ENSGALG00000004763Gallus gallus
 P30838ENSG00000108602Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P47740 / Aldh3a2 / Fatty aldehyde dehydrogenase / P51648* / aldehyde dehydrogenase 3 family member A2*ENSMUSG0000001002564
E9Q3E1 / Aldh3b2 / Aldehyde dehydrogenase family 3 member B2 / P48448* / aldehyde dehydrogenase 3 family member B2*ENSMUSG0000007529653
J3QMK6 / Aldh3b3 / Aldehyde dehydrogenase family 3 member B3 / P48448* / ALDH3B2* / aldehyde dehydrogenase 3 family member B2*ENSMUSG0000003726352
Q80VQ0 / Aldh3b1 / Aldehyde dehydrogenase family 3 member B1 / P43353* / aldehyde dehydrogenase 3 family member B1*ENSMUSG0000002488551


Protein motifs (from Interpro)
Interpro ID Name
 IPR012394  Aldehyde dehydrogenase NAD(P)-dependent
 IPR015590  Aldehyde dehydrogenase domain
 IPR016160  Aldehyde dehydrogenase, cysteine active site
 IPR016161  Aldehyde/histidinol dehydrogenase
 IPR016162  Aldehyde dehydrogenase, N-terminal
 IPR029510  Aldehyde dehydrogenase, glutamic acid active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0006081 cellular aldehyde metabolic process ISS
 biological_processGO:0007568 aging IEA
 biological_processGO:0007584 response to nutrient IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0014070 response to organic cyclic compound IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0051384 response to glucocorticoid IEA
 biological_processGO:0051591 response to cAMP IEA
 biological_processGO:0055114 oxidation-reduction process ISO
 cellular_componentGO:0005737 cytoplasm NAS
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016021 integral component of membrane IDA
 molecular_functionGO:0004028 3-chloroallyl aldehyde dehydrogenase activity IEA
 molecular_functionGO:0004029 aldehyde dehydrogenase (NAD) activity IEA
 molecular_functionGO:0004030 aldehyde dehydrogenase [NAD(P)+] activity IEA
 molecular_functionGO:0008106 alcohol dehydrogenase (NADP+) activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IDA
 molecular_functionGO:0018479 benzaldehyde dehydrogenase (NAD+) activity IEA


Pathways (from Reactome)
Pathway description
Phase I - Functionalization of compounds


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified

 MP:0003961 decreased lean body mass "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
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Allelic Composition: Adipor1tm1b(EUCOMM)Hmgu/Adipor1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Adipor1tm1b(EUCOMM)Hmgu/H

 MP:0010124 decreased bone mineral content "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Adipor1tm1b(EUCOMM)Hmgu/Adipor1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Adipor1tm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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