ENSMUSG00000024885


Mus musculus

Features
Gene ID: ENSMUSG00000024885
  
Biological name :Aldh3b1
  
Synonyms : Aldehyde dehydrogenase family 3 member B1 / Aldh3b1 / Q80VQ0
  
Possible biological names infered from orthology : aldehyde dehydrogenase 3 family member B1 / P43353
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: A
Gene start: 3913493
Gene end: 3929761
  
Corresponding Affymetrix probe sets: 10464560 (MoGene1.0st)   1452301_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000056276
NCBI entrez gene - 67689     See in Manteia.
MGI - MGI:1914939
RefSeq - XM_006531830
RefSeq - NM_026316
RefSeq Peptide - NP_080592
swissprot - Q3TX25
swissprot - Q80VQ0
Ensembl - ENSMUSG00000024885
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aldh3b1ENSDARG00000013839Danio rerio
 ENSGALG00000036044Gallus gallus
 P43353ENSG00000006534Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
J3QMK6 / Aldh3b3 / Aldehyde dehydrogenase family 3 member B3 / P48448* / ALDH3B2* / aldehyde dehydrogenase 3 family member B2*ENSMUSG0000003726382
E9Q3E1 / Aldh3b2 / Aldehyde dehydrogenase family 3 member B2 / P48448* / aldehyde dehydrogenase 3 family member B2*ENSMUSG0000007529680
P47740 / Aldh3a2 / Fatty aldehyde dehydrogenase / P51648* / aldehyde dehydrogenase 3 family member A2*ENSMUSG0000001002551
P47739 / Aldh3a1 / Mus musculus aldehyde dehydrogenase family 3, subfamily A1 (Aldh3a1), transcript variant 3, mRNA. / P30838* / aldehyde dehydrogenase 3 family member A1*ENSMUSG0000001910250


Protein motifs (from Interpro)
Interpro ID Name
 IPR012394  Aldehyde dehydrogenase NAD(P)-dependent
 IPR015590  Aldehyde dehydrogenase domain
 IPR016160  Aldehyde dehydrogenase, cysteine active site
 IPR016161  Aldehyde/histidinol dehydrogenase
 IPR016162  Aldehyde dehydrogenase, N-terminal
 IPR029510  Aldehyde dehydrogenase, glutamic acid active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006068 ethanol catabolic process IEA
 biological_processGO:0006081 cellular aldehyde metabolic process IC
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0034599 cellular response to oxidative stress IEA
 biological_processGO:0046185 aldehyde catabolic process ISO
 biological_processGO:0055114 oxidation-reduction process ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004029 aldehyde dehydrogenase (NAD) activity IDA
 molecular_functionGO:0004030 aldehyde dehydrogenase [NAD(P)+] activity ISO
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000063 reduced bone density "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315]
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Allelic Composition: Adipor1tm1b(EUCOMM)Hmgu/Adipor1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Adipor1tm1b(EUCOMM)Hmgu/H

 MP:0000222 decreased neutrophil count "fewer than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Adipor1tm1b(EUCOMM)Hmgu/Adipor1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Adipor1tm1b(EUCOMM)Hmgu/H

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Adipor1tm1b(EUCOMM)Hmgu/Adipor1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Adipor1tm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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