ENSG00000025293


Homo sapiens

Features
Gene ID: ENSG00000025293
  
Biological name :PHF20
  
Synonyms : PHD finger protein 20 / PHF20 / Q9BVI0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q11.22
Gene start: 35771974
Gene end: 35950381
  
Corresponding Affymetrix probe sets: 1569906_s_at (Human Genome U133 Plus 2.0 Array)   206567_s_at (Human Genome U133 Plus 2.0 Array)   209422_at (Human Genome U133 Plus 2.0 Array)   209423_s_at (Human Genome U133 Plus 2.0 Array)   235389_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000391915
Ensembl peptide - ENSP00000363124
Ensembl peptide - ENSP00000404455
Ensembl peptide - ENSP00000413712
Ensembl peptide - ENSP00000341900
Ensembl peptide - ENSP00000363112
NCBI entrez gene - 51230     See in Manteia.
OMIM - 610335
RefSeq - XM_017027871
RefSeq - XM_017027864
RefSeq - XM_017027865
RefSeq - XM_017027866
RefSeq - XM_017027867
RefSeq - XM_017027868
RefSeq - XM_017027869
RefSeq - XM_017027870
RefSeq - NM_016436
RefSeq - XM_005260421
RefSeq - XM_011528843
RefSeq - XM_011528844
RefSeq Peptide - NP_057520
swissprot - F8WCQ1
swissprot - B0QYY0
swissprot - B0QZ19
swissprot - Q5JWZ0
swissprot - Q5JXL1
swissprot - Q9BVI0
Ensembl - ENSG00000025293
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 phf20aENSDARG00000002750Danio rerio
 phf20bENSDARG00000038737Danio rerio
 PHF20ENSGALG00000001522Gallus gallus
 Phf20ENSMUSG00000038116Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A8MW92 / PHF20L1 / PHD finger protein 20 like 1ENSG0000012929233


Protein motifs (from Interpro)
Interpro ID Name
 IPR001965  Zinc finger, PHD-type
 IPR002999  Tudor domain
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR022255  Domain of unknown function DUF3776


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0043981 histone H4-K5 acetylation IDA
 biological_processGO:0043982 histone H4-K8 acetylation IDA
 biological_processGO:0043984 histone H4-K16 acetylation IDA
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator TAS
 cellular_componentGO:0000123 histone acetyltransferase complex IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0031965 nuclear membrane IDA
 cellular_componentGO:0071339 MLL1 complex IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043995 histone acetyltransferase activity (H4-K5 specific) IDA
 molecular_functionGO:0043996 histone acetyltransferase activity (H4-K8 specific) IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046972 histone acetyltransferase activity (H4-K16 specific) IDA


Pathways (from Reactome)
Pathway description
HATs acetylate histones
Regulation of TP53 Degradation
Regulation of TP53 Activity through Association with Co-factors
Stabilization of p53


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000141510 TP53 / P04637 / tumor protein p53  / complex / reaction
 ENSG00000142208 AKT1 / P31749 / AKT serine/threonine kinase 1  / reaction






 

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