ENSG00000041880


Homo sapiens

Features
Gene ID: ENSG00000041880
  
Biological name :PARP3
  
Synonyms : PARP3 / poly(ADP-ribose) polymerase family member 3 / Q9Y6F1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p21.2
Gene start: 51942345
Gene end: 51948867
  
Corresponding Affymetrix probe sets: 209940_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000395951
Ensembl peptide - ENSP00000417625
Ensembl peptide - ENSP00000417396
Ensembl peptide - ENSP00000401511
Ensembl peptide - ENSP00000381740
NCBI entrez gene - 10039     See in Manteia.
OMIM - 607726
RefSeq - XM_017005490
RefSeq - NM_001003931
RefSeq - NM_005485
RefSeq - XM_005264779
RefSeq Peptide - NP_001003931
RefSeq Peptide - NP_005476
swissprot - C9J9C7
swissprot - A0A024R2X5
swissprot - F8WAY7
swissprot - Q9Y6F1
Ensembl - ENSG00000041880
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 parp3ENSDARG00000003961Danio rerio
 PARP3ENSGALG00000004517Gallus gallus
 Parp3ENSMUSG00000023249Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PARP2 / Q9UGN5 / poly(ADP-ribose) polymerase 2ENSG0000012948434
PARP1 / P09874 / poly(ADP-ribose) polymerase 1ENSG0000014379931


Protein motifs (from Interpro)
Interpro ID Name
 IPR004102  Poly(ADP-ribose) polymerase, regulatory domain
 IPR008893  WGR domain
 IPR012317  Poly(ADP-ribose) polymerase, catalytic domain
 IPR031275  Poly [ADP-ribose] polymerase 3
 IPR036616  Poly(ADP-ribose) polymerase, regulatory domain superfamily
 IPR036930  WGR domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000723 telomere maintenance IMP
 biological_processGO:0006273 lagging strand elongation IBA
 biological_processGO:0006281 DNA repair TAS
 biological_processGO:0006302 double-strand break repair IMP
 biological_processGO:0006471 protein ADP-ribosylation TAS
 biological_processGO:0051103 DNA ligation involved in DNA repair IBA
 biological_processGO:0051106 positive regulation of DNA ligation IGI
 biological_processGO:0060236 regulation of mitotic spindle organization IMP
 biological_processGO:1990166 protein localization to site of double-strand break IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005814 centriole IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0035861 site of double-strand break IDA
 molecular_functionGO:0003824 catalytic activity TAS
 molecular_functionGO:0003910 DNA ligase (ATP) activity IBA
 molecular_functionGO:0003950 NAD+ ADP-ribosyltransferase activity IDA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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