ENSG00000049249


Homo sapiens

Features
Gene ID: ENSG00000049249
  
Biological name :TNFRSF9
  
Synonyms : Q07011 / TNF receptor superfamily member 9 / TNFRSF9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.23
Gene start: 7915894
Gene end: 7943165
  
Corresponding Affymetrix probe sets: 207536_s_at (Human Genome U133 Plus 2.0 Array)   211786_at (Human Genome U133 Plus 2.0 Array)   238950_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000366729
Ensembl peptide - ENSP00000464978
Ensembl peptide - ENSP00000465272
Ensembl peptide - ENSP00000478699
NCBI entrez gene - 3604     See in Manteia.
OMIM - 602250
RefSeq - XM_011541386
RefSeq - NM_001561
RefSeq - XM_006710618
RefSeq Peptide - NP_001552
swissprot - Q07011
swissprot - K7EJQ2
swissprot - K7EJ11
Ensembl - ENSG00000049249
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tnfrsf9aENSDARG00000060498Danio rerio
 tnfrsf9bENSDARG00000090728Danio rerio
 P20334ENSMUSG00000028965Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001368  TNFR/NGFR cysteine-rich region
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR020413  Tumour necrosis factor receptor 9
 IPR034020  Tumour necrosis factor receptor 9, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process TAS
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IBA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0008285 negative regulation of cell proliferation TAS
 biological_processGO:0032496 response to lipopolysaccharide IBA
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway TAS
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0070207 protein homotrimerization IEA
 biological_processGO:0097190 apoptotic signaling pathway IBA
 biological_processGO:2001180 negative regulation of interleukin-10 secretion IEA
 biological_processGO:2001183 negative regulation of interleukin-12 secretion IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005031 tumor necrosis factor-activated receptor activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0019955 cytokine binding IEA


Pathways (from Reactome)
Pathway description
TNFs bind their physiological receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000049249 Q07011 / TNFRSF9 / TNF receptor superfamily member 9  / complex / reaction
 ENSG00000125657 P41273 / TNFSF9 / TNF superfamily member 9  / reaction / complex






 

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