ENSMUSG00000028965


Mus musculus

Features
Gene ID: ENSMUSG00000028965
  
Biological name :Tnfrsf9
  
Synonyms : P20334 / Tnfrsf9 / tumor necrosis factor receptor superfamily, member 9
  
Possible biological names infered from orthology : Q07011 / TNF receptor superfamily member 9
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: E2
Gene start: 150914562
Gene end: 150946102
  
Corresponding Affymetrix probe sets: 10510580 (MoGene1.0st)   1428034_a_at (Mouse Genome 430 2.0 Array)   1460469_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000111961
Ensembl peptide - ENSMUSP00000122917
Ensembl peptide - ENSMUSP00000120761
Ensembl peptide - ENSMUSP00000117860
Ensembl peptide - ENSMUSP00000030808
Ensembl peptide - ENSMUSP00000059684
Ensembl peptide - ENSMUSP00000101296
Ensembl peptide - ENSMUSP00000101297
NCBI entrez gene - 21942     See in Manteia.
MGI - MGI:1101059
RefSeq - NM_001077509
RefSeq - XM_011250228
RefSeq - NM_011612
RefSeq - NM_001077508
RefSeq Peptide - NP_001070976
RefSeq Peptide - NP_001070977
RefSeq Peptide - NP_035742
swissprot - Q8R037
swissprot - A2A887
swissprot - P20334
swissprot - Q3U3R1
swissprot - A2A886
swissprot - A2A888
Ensembl - ENSMUSG00000028965
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tnfrsf9aENSDARG00000060498Danio rerio
 tnfrsf9bENSDARG00000090728Danio rerio
 Q07011ENSG00000049249Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001368  TNFR/NGFR cysteine-rich region
 IPR020413  Tumour necrosis factor receptor 9
 IPR034020  Tumour necrosis factor receptor 9, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IBA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0032496 response to lipopolysaccharide IBA
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway IEA
 biological_processGO:0042127 regulation of cell proliferation IDA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0070207 protein homotrimerization IDA
 biological_processGO:0097190 apoptotic signaling pathway IBA
 biological_processGO:2001180 negative regulation of interleukin-10 secretion IMP
 biological_processGO:2001183 negative regulation of interleukin-12 secretion IMP
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005031 tumor necrosis factor-activated receptor activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0019955 cytokine binding IPI


Pathways (from Reactome)
Pathway description
TNFs bind their physiological receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000062 increased bone density "increased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295]
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Allelic Composition: Tmem79tm1.1(KOMP)Wtsi/Tmem79tm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmem79tm1.1(KOMP)Wtsi/J

 MP:0000523 cortical glomerulopathies "any disease of the capillary plexus in the kidney cortex" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:63229]
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Allelic Composition: Faslpr/Faslpr,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: MRL.Cg-Tnfrsf9tm1Byk Faslpr

 MP:0000691 enlarged spleen "increased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Faslpr/Faslpr,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: MRL.Cg-Tnfrsf9tm1Byk Faslpr

 MP:0000702 enlarged lymph nodes "lymph nodes of increased size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Faslpr/Faslpr,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: MRL.Cg-Tnfrsf9tm1Byk Faslpr

 MP:0001212 skin lesions "focal patches of inflammation on the skin" [J:30162]
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Allelic Composition: Faslpr/Faslpr,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: MRL.Cg-Tnfrsf9tm1Byk Faslpr

 MP:0001346 abnormal lacrimal gland morphology "malformation of the glands that secrete tears" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator]
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Allelic Composition: Faslpr/Faslpr,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: MRL.Cg-Tnfrsf9tm1Byk Faslpr

 MP:0001806 decreased IgM "less than normal immunoglobulin class M level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Baxtm1Sjk/Baxtm1Sjk
Genetic Background: involves: 129X1/SvJ

 MP:0002078 abnormal glucose homeostasis "anomaly in the state of equilibrium or processing in the body with respect to glucose in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Serpina12tm1Jwada/Serpina12+
Genetic Background: B6JJcl.129P2-Serpina12tm1Jwada

Allelic Composition: Tnfrsf9em2Ygch/Tnfrsf9em2Ygch
Genetic Background: NOD/ShiLtDvs-Tnfrsf9em2Ygch

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Faslpr/Faslpr,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: MRL.Cg-Tnfrsf9tm1Byk Faslpr

 MP:0002135 abnormal kidney morphology "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Faslpr/Faslpr
Genetic Background: B6.Cg-Apoetm1Unc Faslpr

 MP:0002177 abnormal outer ear morphology "malformation or malfunction of any components of the auricles or external acoustic meatus" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Faslpr/Faslpr,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: MRL.Cg-Tnfrsf9tm1Byk Faslpr

 MP:0002444 abnormal T cell physiology "anomalous response of T lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Serpina12tm1Jwada/Serpina12+
Genetic Background: B6JJcl.129P2-Serpina12tm1Jwada

Allelic Composition: Tnfrsf9em2Ygch/Tnfrsf9em2Ygch
Genetic Background: NOD/ShiLtDvs-Tnfrsf9em2Ygch

 MP:0002461 increased circulating immunoglobulin concentration "greater than normal immunoglobulin level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Faslpr/Faslpr,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: MRL.Cg-Tnfrsf9tm1Byk Faslpr

 MP:0002490 abnormal circulating immunoglobulin concentration "deviation from the normal levels of glycoproteins present in the blood and other tissue, often functioning as antibodies" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Tubb3tm1.1Ece/Tubb3+
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0002495 increased IgA "greater than normal immunoglobulin class A level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Tubb3tm1.1Ece/Tubb3+
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0003795 abnormal bone structure 
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Allelic Composition: Tmem79tm1.1(KOMP)Wtsi/Tmem79tm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmem79tm1.1(KOMP)Wtsi/J

 MP:0004031 insulitis "a histologic change in the islets of Langerhans characterized by edema and the infiltration of small numbers of white blood cells" [rbabiuk:Randall Babiuk, Mouse Genome Informatics Curator]
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Allelic Composition: Serpina12tm1Jwada/Serpina12+
Genetic Background: B6JJcl.129P2-Serpina12tm1Jwada

Allelic Composition: Tnfrsf9em2Ygch/Tnfrsf9em2Ygch
Genetic Background: NOD/ShiLtDvs-Tnfrsf9em2Ygch

 MP:0004794 increased anti-nuclear antigen antibody level "elevated level of antibodies to nuclear antigens present in the sera" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Faslpr/Faslpr,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: MRL.Cg-Tnfrsf9tm1Byk Faslpr

 MP:0004801 increased susceptibility to systemic lupus erythematosus "greater likelihood that an organism will develop inflammatory connective tissue symptoms characteristic of lupus including skin rash, arthritis and inflammation of different organs" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Faslpr/Faslpr,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: MRL.Cg-Tnfrsf9tm1Byk Faslpr

 MP:0004816 abnormal class switch recombination "anomaly in the rearrangement of the heavy chain genes of differentiating B cells such that the initially encoded heavy chain IgM molecule is altered to one encoding IgG, IgA or IgE; normally, this allows the body to produce antibodies with different effector functions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cd28tm1Pjl/Cd28tm1Pjl,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: either: B6.Cg-Cd28tm1Pjl Tnfrsf9tm1Byk or C.Cg-Cd28tm1Pjl Tnfrsf9tm1Byk

 MP:0004977 increased B-1 B cell number "greater number of the subset of B cells found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Faslpr/Faslpr,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: MRL.Cg-Tnfrsf9tm1Byk Faslpr

 MP:0005078 abnormal cytotoxic T cell physiology "impaired function of the subset of CD8+ T lymphocytes capable of directly killing appropriately targeted cells " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Baxtm1Sjk/Baxtm1Sjk
Genetic Background: involves: 129X1/SvJ

Allelic Composition: Cd28tm1Pjl/Cd28tm1Pjl,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: either: B6.Cg-Cd28tm1Pjl Tnfrsf9tm1Byk or C.Cg-Cd28tm1Pjl Tnfrsf9tm1Byk

Allelic Composition: Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: C.Cg-Tnfrsf9tm1Byk

 MP:0005090 increased double-negative T cells count "greater than expected numbers of the subset of T cells found in the thymus that express neither CD4 nor CD8" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Faslpr/Faslpr,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: MRL.Cg-Tnfrsf9tm1Byk Faslpr

 MP:0005348 increased T cell proliferation "increased clonal expansion of naive T cells in response to stimuli" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Baxtm1Sjk/Baxtm1Sjk
Genetic Background: involves: 129X1/SvJ

Allelic Composition: Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: C.Cg-Tnfrsf9tm1Byk

 MP:0005616 decreased susceptibility to type IV hypersensitivity reaction "less likelihood of or resistance to developing an antigen-elicited cellular immune reaction that results in tissue damage, but does not require Ab participation; the response is seen at the area of contact" [Pathology:ISBN 0-397-51047-0, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cd28tm1Pjl/Cd28tm1Pjl,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: either: B6.Cg-Cd28tm1Pjl Tnfrsf9tm1Byk or C.Cg-Cd28tm1Pjl Tnfrsf9tm1Byk

 MP:0006410 abnormal common myeloid progenitor cell morphology "anomaly in the structure of the hematopoietic stem cells that are capable of forming any of the myeloid lineage cells (erythrocytes, granulocytes, thrombocytes, monocytes, and mast cells) but not cells of the lymphoid lineage" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Baxtm1Sjk/Baxtm1Sjk
Genetic Background: involves: 129X1/SvJ

Allelic Composition: Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: C.Cg-Tnfrsf9tm1Byk

 MP:0008051 abnormal memory T cell physiology "any functional anomaly of the set of long-lived T cells differentiated from T cells activated by a specific antigen encountered during a past immune response" [adiehl:Alex Diehl_MGI GO curator, Biology-Online.org:http://www.biology-online.org/, MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Apoetm1Bres/Apoetm1Bres
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0008074 increased CD4-positive T cell number "greater number of the subset of T lymphocytes that carry the CD4 marker, recognize intravesicular peptides bound to MHC class-II molecules, and turn on antibody production" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Faslpr/Faslpr,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: MRL.Cg-Tnfrsf9tm1Byk Faslpr

 MP:0008206 increased B-2 cell number "greater number of conventional B cells subject to antigenic stimulation and dependent on T cell help and with a distinct surface marker expression pattern from B-1 B cells" [CL:0000822, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:11861604]
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Allelic Composition: Faslpr/Faslpr,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: MRL.Cg-Tnfrsf9tm1Byk Faslpr

 MP:0008481 increased spleen germinal center number "greater number of spleen secondary B follicles where rapid B-cell proliferation, somatic hypermutation, and selection for antigen binding occurs" [PMID:17495967]
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Allelic Composition: Faslpr/Faslpr,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: MRL.Cg-Tnfrsf9tm1Byk Faslpr

 MP:0008495 decreased IgG1 level "less than normal immunoglobulin class G1 level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
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Allelic Composition: Cd28tm1Pjl/Cd28tm1Pjl,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: either: B6.Cg-Cd28tm1Pjl Tnfrsf9tm1Byk or C.Cg-Cd28tm1Pjl Tnfrsf9tm1Byk

 MP:0008496 decreased IgG2a level "less than normal immunoglobulin class G2a level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
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Allelic Composition: Baxtm1Sjk/Baxtm1Sjk
Genetic Background: involves: 129X1/SvJ

Allelic Composition: Cd28tm1Pjl/Cd28tm1Pjl,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: either: B6.Cg-Cd28tm1Pjl Tnfrsf9tm1Byk or C.Cg-Cd28tm1Pjl Tnfrsf9tm1Byk

Allelic Composition: Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: C.Cg-Tnfrsf9tm1Byk

 MP:0008498 decreased IgG3 level "less than normal immunoglobulin class G3 level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
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Allelic Composition: Baxtm1Sjk/Baxtm1Sjk
Genetic Background: involves: 129X1/SvJ

Allelic Composition: Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: C.Cg-Tnfrsf9tm1Byk

 MP:0008500 increased IgG2a level "greater than normal immunoglobulin class G2a level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
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Allelic Composition: Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: C.Cg-Tnfrsf9tm1Byk

 MP:0008501 increased IgG2b level "greater than normal immunoglobulin class G2b level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
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Allelic Composition: Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: C.Cg-Tnfrsf9tm1Byk

 MP:0008567 decreased interferon-gamma secretion "reduction in the production or release of the major interferon produced by mitogenically or antigenically stimulated lymphocytes that is involved in immunoregulation" [MESH:D12.644.276.374.440.893]
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Allelic Composition: Baxtm1Sjk/Baxtm1Sjk
Genetic Background: involves: 129X1/SvJ

Allelic Composition: Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: C.Cg-Tnfrsf9tm1Byk

 MP:0008664 decreased interleukin-12 secretion "reduction in the production or release of a heterodimeric cytokine that plays a role in innate and adaptive immune responses; it is produced by dendritic cells, macrophages and a variety of other immune cells and plays a role in the stimulation of interferon-gamma production by T-cells and natural killer cells" [MESH:D12.644.276.374.465.512]
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Allelic Composition: Cd28tm1Pjl/Cd28tm1Pjl,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: either: B6.Cg-Cd28tm1Pjl Tnfrsf9tm1Byk or C.Cg-Cd28tm1Pjl Tnfrsf9tm1Byk

Allelic Composition: Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: C.Cg-Tnfrsf9tm1Byk

 MP:0008688 decreased interleukin-2 secretion "reduction in the production or release of a soluble substance elaborated by antigen- or mitogen-stimulated T-cells which induces DNA synthesis in naive lymphocytes" [MESH:D12.644.276.374.465.502]
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Allelic Composition: Baxtm1Sjk/Baxtm1Sjk
Genetic Background: involves: 129X1/SvJ

Allelic Composition: Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: C.Cg-Tnfrsf9tm1Byk

 MP:0008699 increased interleukin-4 secretion "increase in the production or release of a soluble factor produced by activated T-cells that induces the expression of MHC class II genes and FC receptors on B-cells and causes their proliferation and differentiation; it also acts on T-cells, mast cells and several other hematopoietic lineage cells" [MESH:D12.644.276.374.465.504]
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Allelic Composition: Faslpr/Faslpr,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: MRL.Cg-Tnfrsf9tm1Byk Faslpr

 MP:0008700 decreased interleukin-4 secretion "reduction in the production or release of a soluble factor produced by activated T-cells that induces the expression of MHC class II genes and FC receptors on B-cells and causes their proliferation and differentiation; it also acts on T-cells, mast cells and several other hematopoietic lineage cells" [MESH:D12.644.276.374.465.504]
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Allelic Composition: Baxtm1Sjk/Baxtm1Sjk
Genetic Background: involves: 129X1/SvJ

Allelic Composition: Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: C.Cg-Tnfrsf9tm1Byk

 MP:0008880 lacrimal gland inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the glands that secrete tears" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Faslpr/Faslpr,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: MRL.Cg-Tnfrsf9tm1Byk Faslpr

 MP:0009335 decreased splenocyte proliferation "reduction in the expansion rate of a splenocyte cell population by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cd28tm1Pjl/Cd28tm1Pjl,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: either: B6.Cg-Cd28tm1Pjl Tnfrsf9tm1Byk or C.Cg-Cd28tm1Pjl Tnfrsf9tm1Byk

 MP:0009336 increased splenocyte proliferation "increase in the expansion rate of a splenocyte cell population by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: C.Cg-Tnfrsf9tm1Byk

 MP:0010123 increased bone mineral content "elevation in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tmem79tm1.1(KOMP)Wtsi/Tmem79tm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmem79tm1.1(KOMP)Wtsi/J

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Tmod2tm1b(KOMP)Wtsi/Tmod2tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmod2tm1b(KOMP)Wtsi/J

 MP:0013452 increased lacrimal gland apoptosis " increase in the number of cells of the lacrimal gland undergoing programmed cell death" [MGI:Anna]
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Allelic Composition: Faslpr/Faslpr,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: MRL.Cg-Tnfrsf9tm1Byk Faslpr

 MP:0020518 renal glomerular protein deposits "any anomalous accumulation of protein in the renal glomerulus" [HP:0030949]
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Allelic Composition: Faslpr/Faslpr,Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
Genetic Background: MRL.Cg-Tnfrsf9tm1Byk Faslpr

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000028965 P20334 / Tnfrsf9 / tumor necrosis factor receptor superfamily, member 9 / Q07011* / TNF receptor superfamily member 9*  / complex / reaction
 ENSMUSG00000035678 P41274 / Tnfsf9 / tumor necrosis factor (ligand) superfamily, member 9 / P41273* / TNF superfamily member 9*  / reaction / complex






 

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