ENSG00000125657


Homo sapiens

Features
Gene ID: ENSG00000125657
  
Biological name :TNFSF9
  
Synonyms : P41273 / TNFSF9 / TNF superfamily member 9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.3
Gene start: 6530999
Gene end: 6535928
  
Corresponding Affymetrix probe sets: 206907_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000245817
NCBI entrez gene - 8744     See in Manteia.
OMIM - 606182
RefSeq - NM_003811
RefSeq Peptide - NP_003802
swissprot - A0A0U5J8I0
swissprot - P41273
Ensembl - ENSG00000125657
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P41274ENSMUSG00000035678Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006052  Tumour necrosis factor domain
 IPR008983  Tumour necrosis factor-like domain superfamily
 IPR021184  Tumour necrosis factor, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process TAS
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway TAS
 biological_processGO:0042104 positive regulation of activated T cell proliferation IBA
 biological_processGO:0045585 positive regulation of cytotoxic T cell differentiation IBA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005102 signaling receptor binding TAS
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005164 tumor necrosis factor receptor binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0032813 tumor necrosis factor receptor superfamily binding IBA


Pathways (from Reactome)
Pathway description
TNFs bind their physiological receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000125657 P41273 / TNFSF9 / TNF superfamily member 9  / complex
 ENSG00000049249 Q07011 / TNFRSF9 / TNF receptor superfamily member 9  / reaction / complex






 

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