ENSG00000063438


Homo sapiens

Features
Gene ID: ENSG00000063438
  
Biological name :AHRR
  
Synonyms : A9YTQ3 / AHRR / aryl-hydrocarbon receptor repressor
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: p15.33
Gene start: 304176
Gene end: 438291
  
Corresponding Affymetrix probe sets: 229354_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000424601
Ensembl peptide - ENSP00000430914
Ensembl peptide - ENSP00000430842
Ensembl peptide - ENSP00000429944
Ensembl peptide - ENSP00000428893
Ensembl peptide - ENSP00000426932
Ensembl peptide - ENSP00000426076
Ensembl peptide - ENSP00000424880
Ensembl peptide - ENSP00000323816
NCBI entrez gene - 57491     See in Manteia.
OMIM - 606517
RefSeq - NM_020731
RefSeq - NM_001242412
RefSeq Peptide - NP_065782
RefSeq Peptide - NP_001229341
swissprot - A9YTQ3
swissprot - D6RF73
swissprot - G3V143
swissprot - H0YA43
swissprot - E5RFG4
swissprot - E5RGQ2
swissprot - E5RHE0
swissprot - D6RE68
Ensembl - ENSG00000063438
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ahrrbENSDARG00000052618Danio rerio
 CABZ01114318.1ENSDARG00000099702Danio rerio
 AHRRENSGALG00000013402Gallus gallus
 AhrrENSMUSG00000021575Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AC019117.3ENSG0000028332127
AHR / P35869 / aryl hydrocarbon receptorENSG0000010654627


Protein motifs (from Interpro)
Interpro ID Name
 IPR000014  PAS domain
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR013767  PAS fold
 IPR035965  PAS domain superfamily
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006805 xenobiotic metabolic process TAS
 biological_processGO:0009410 response to xenobiotic stimulus IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
PPARA activates gene expression
Aryl hydrocarbon receptor signalling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000172379 ARNT2 / Q9HBZ2 / aryl hydrocarbon receptor nuclear translocator 2  / complex / reaction
 ENSG00000143437 ARNT / P27540 / aryl hydrocarbon receptor nuclear translocator  / reaction / complex






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr