ENSG00000065485


Homo sapiens

Features
Gene ID: ENSG00000065485
  
Biological name :PDIA5
  
Synonyms : PDIA5 / protein disulfide isomerase family A member 5 / Q14554
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q21.1
Gene start: 123067062
Gene end: 123225227
  
Corresponding Affymetrix probe sets: 203857_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000417199
Ensembl peptide - ENSP00000419946
Ensembl peptide - ENSP00000417520
Ensembl peptide - ENSP00000323313
NCBI entrez gene - 10954     See in Manteia.
OMIM - 616942
RefSeq - NM_006810
RefSeq Peptide - NP_006801
swissprot - C9JY10
swissprot - H7C4F9
swissprot - Q14554
Ensembl - ENSG00000065485
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pdia5ENSDARG00000069242Danio rerio
 PDIA5ENSGALG00000011689Gallus gallus
 Pdia5ENSMUSG00000022844Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8NBS9 / TXNDC5 / thioredoxin domain containing 5ENSG0000023926421
Q8IXB1 / DNAJC10 / DnaJ heat shock protein family (Hsp40) member C10ENSG0000007723220
PDIA6 / Q15084 / protein disulfide isomerase family A member 6ENSG0000014387019


Protein motifs (from Interpro)
Interpro ID Name
 IPR013766  Thioredoxin domain
 IPR017937  Thioredoxin, conserved site
 IPR036249  Thioredoxin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding TAS
 biological_processGO:0034976 response to endoplasmic reticulum stress IBA
 biological_processGO:0036498 IRE1-mediated unfolded protein response TAS
 biological_processGO:0045454 cell redox homeostasis IEA
 biological_processGO:0055114 oxidation-reduction process TAS
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 molecular_functionGO:0003756 protein disulfide isomerase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015037 peptide disulfide oxidoreductase activity IDA
 molecular_functionGO:0016491 oxidoreductase activity TAS
 molecular_functionGO:0016853 isomerase activity IEA


Pathways (from Reactome)
Pathway description
XBP1(S) activates chaperone genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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