ENSG00000239264


Homo sapiens

Features
Gene ID: ENSG00000239264
  
Biological name :TXNDC5
  
Synonyms : Q8NBS9 / thioredoxin domain containing 5 / TXNDC5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p24.3
Gene start: 7881517
Gene end: 7910814
  
Corresponding Affymetrix probe sets: 221253_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000420784
Ensembl peptide - ENSP00000369081
NCBI entrez gene - 81567     See in Manteia.
OMIM - 616412
RefSeq - NM_001145549
RefSeq - NM_030810
RefSeq Peptide - NP_001139021
RefSeq Peptide - NP_110437
swissprot - Q8NBS9
swissprot - A0A024QZV0
Ensembl - ENSG00000239264
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 txndc5ENSDARG00000009342Danio rerio
 TXNDC5ENSGALG00000012784Gallus gallus
 Q91W90ENSMUSG00000038991Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8IXB1 / DNAJC10 / DnaJ heat shock protein family (Hsp40) member C10ENSG0000007723225
PDIA5 / Q14554 / protein disulfide isomerase family A member 5ENSG0000006548525
PDIA6 / Q15084 / protein disulfide isomerase family A member 6ENSG0000014387022


Protein motifs (from Interpro)
Interpro ID Name
 IPR005788  Disulphide isomerase
 IPR013766  Thioredoxin domain
 IPR017937  Thioredoxin, conserved site
 IPR036249  Thioredoxin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IBA
 biological_processGO:0034976 response to endoplasmic reticulum stress IBA
 biological_processGO:0043066 negative regulation of apoptotic process TAS
 biological_processGO:0043277 apoptotic cell clearance IBA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0045454 cell redox homeostasis IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005783 endoplasmic reticulum TAS
 cellular_componentGO:0005788 endoplasmic reticulum lumen IEA
 cellular_componentGO:0035578 azurophil granule lumen TAS
 cellular_componentGO:0043202 lysosomal lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003756 protein disulfide isomerase activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016853 isomerase activity IEA


Pathways (from Reactome)
Pathway description
Lysosome Vesicle Biogenesis
Golgi Associated Vesicle Biogenesis
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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