ENSG00000065621


Homo sapiens

Features
Gene ID: ENSG00000065621
  
Biological name :GSTO2
  
Synonyms : glutathione S-transferase omega 2 / GSTO2 / Q9H4Y5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q25.1
Gene start: 104268873
Gene end: 104304945
  
Corresponding Affymetrix probe sets: 227163_at (Human Genome U133 Plus 2.0 Array)   229155_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000345023
Ensembl peptide - ENSP00000358721
Ensembl peptide - ENSP00000390986
NCBI entrez gene - 119391     See in Manteia.
OMIM - 612314
RefSeq - XM_011539273
RefSeq - NM_001191013
RefSeq - NM_001191014
RefSeq - NM_001191015
RefSeq - NM_183239
RefSeq - XM_006717624
RefSeq - XM_011539270
RefSeq - XM_011539271
RefSeq Peptide - NP_001177942
RefSeq Peptide - NP_001177943
RefSeq Peptide - NP_001177944
RefSeq Peptide - NP_899062
swissprot - Q9H4Y5
Ensembl - ENSG00000065621
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gsto1ENSDARG00000022183Danio rerio
 gsto2ENSDARG00000033285Danio rerio
 GSTO1ENSGALG00000008409Gallus gallus
 Gsto2ENSMUSG00000025069Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GSTO1 / P78417 / glutathione S-transferase omega 1ENSG0000014883464


Protein motifs (from Interpro)
Interpro ID Name
 IPR004045  Glutathione S-transferase, N-terminal
 IPR005442  Glutathione S-transferase, omega-class
 IPR010987  Glutathione S-transferase, C-terminal-like
 IPR036249  Thioredoxin-like superfamily
 IPR036282  Glutathione S-transferase, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006749 glutathione metabolic process IBA
 biological_processGO:0006805 xenobiotic metabolic process IDA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009407 toxin catabolic process IBA
 biological_processGO:0019852 L-ascorbic acid metabolic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0071243 cellular response to arsenic-containing substance IDA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 biological_processGO:1901687 glutathione derivative biosynthetic process TAS
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004364 glutathione transferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0045174 glutathione dehydrogenase (ascorbate) activity TAS
 molecular_functionGO:0050610 methylarsonate reductase activity IEA


Pathways (from Reactome)
Pathway description
Glutathione conjugation
Vitamin C (ascorbate) metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000065621 GSTO2 / Q9H4Y5 / glutathione S-transferase omega 2  / complex






 

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