ENSG00000148834


Homo sapiens

Features
Gene ID: ENSG00000148834
  
Biological name :GSTO1
  
Synonyms : glutathione S-transferase omega 1 / GSTO1 / P78417
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q25.1
Gene start: 104235356
Gene end: 104267459
  
Corresponding Affymetrix probe sets: 1557915_s_at (Human Genome U133 Plus 2.0 Array)   201470_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000358727
Ensembl peptide - ENSP00000406708
Ensembl peptide - ENSP00000441488
Ensembl peptide - ENSP00000358724
Ensembl peptide - ENSP00000405325
NCBI entrez gene - 9446     See in Manteia.
OMIM - 605482
RefSeq - NM_001191003
RefSeq - NM_001191002
RefSeq - NM_004832
RefSeq Peptide - NP_001177931
RefSeq Peptide - NP_001177932
RefSeq Peptide - NP_004823
swissprot - P78417
swissprot - Q5TA01
swissprot - Q5TA02
swissprot - V9HWG9
Ensembl - ENSG00000148834
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gsto1ENSDARG00000022183Danio rerio
 gsto2ENSDARG00000033285Danio rerio
 GSTO1ENSGALG00000008409Gallus gallus
 Gsto1ENSMUSG00000025068Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GSTO2 / Q9H4Y5 / glutathione S-transferase omega 2ENSG0000006562164


Protein motifs (from Interpro)
Interpro ID Name
 IPR004045  Glutathione S-transferase, N-terminal
 IPR004046  Glutathione S-transferase, C-terminal
 IPR005442  Glutathione S-transferase, omega-class
 IPR010987  Glutathione S-transferase, C-terminal-like
 IPR036249  Thioredoxin-like superfamily
 IPR036282  Glutathione S-transferase, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006749 glutathione metabolic process IBA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009407 toxin catabolic process IBA
 biological_processGO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum IDA
 biological_processGO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion IC
 biological_processGO:0014810 positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion IC
 biological_processGO:0019852 L-ascorbic acid metabolic process IDA
 biological_processGO:0032259 methylation TAS
 biological_processGO:0035722 interleukin-12-mediated signaling pathway TAS
 biological_processGO:0042178 xenobiotic catabolic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity IDA
 biological_processGO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity IDA
 biological_processGO:0071243 cellular response to arsenic-containing substance IDA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 biological_processGO:1901687 glutathione derivative biosynthetic process TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004364 glutathione transferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0045174 glutathione dehydrogenase (ascorbate) activity IEA
 molecular_functionGO:0050610 methylarsonate reductase activity TAS


Pathways (from Reactome)
Pathway description
Methylation
Glutathione conjugation
Vitamin C (ascorbate) metabolism
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000148834 GSTO1 / P78417 / glutathione S-transferase omega 1  / complex






 

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