ENSMUSG00000025068


Mus musculus

Features
Gene ID: ENSMUSG00000025068
  
Biological name :Gsto1
  
Synonyms : Glutathione S-transferase omega-1 / Gsto1 / O09131
  
Possible biological names infered from orthology : P78417
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: D1
Gene start: 47854970
Gene end: 47864790
  
Corresponding Affymetrix probe sets: 10463836 (MoGene1.0st)   1416531_at (Mouse Genome 430 2.0 Array)   1456036_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026050
NCBI entrez gene - 14873     See in Manteia.
MGI - MGI:1342273
RefSeq - NM_010362
RefSeq Peptide - NP_034492
swissprot - O09131
Ensembl - ENSMUSG00000025068
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gsto1ENSDARG00000022183Danio rerio
 gsto2ENSDARG00000033285Danio rerio
 GSTO1ENSGALG00000008409Gallus gallus
 GSTO1ENSG00000148834Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gsto2 / Q8K2Q2 / Glutathione S-transferase omega-2 / Q9H4Y5*ENSMUSG0000002506957


Protein motifs (from Interpro)
Interpro ID Name
 IPR004045  Glutathione S-transferase, N-terminal
 IPR004046  Glutathione S-transferase, C-terminal
 IPR005442  Glutathione S-transferase, omega-class
 IPR010987  Glutathione S-transferase, C-terminal-like
 IPR036249  Thioredoxin-like superfamily
 IPR036282  Glutathione S-transferase, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006749 glutathione metabolic process IBA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009407 toxin catabolic process IBA
 biological_processGO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum IEA
 biological_processGO:0019852 L-ascorbic acid metabolic process IEA
 biological_processGO:0042178 xenobiotic catabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity IEA
 biological_processGO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity IEA
 biological_processGO:0071243 cellular response to arsenic-containing substance IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004364 glutathione transferase activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016491 oxidoreductase activity ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0045174 glutathione dehydrogenase (ascorbate) activity ISO
 molecular_functionGO:0050610 methylarsonate reductase activity IEA


Pathways (from Reactome)
Pathway description
Methylation
Glutathione conjugation
Vitamin C (ascorbate) metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000025068 Gsto1 / O09131 / Glutathione S-transferase omega-1 / P78417*  / complex






 

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