ENSMUSG00000025069


Mus musculus

Features
Gene ID: ENSMUSG00000025069
  
Biological name :Gsto2
  
Synonyms : Glutathione S-transferase omega-2 / Gsto2 / Q8K2Q2
  
Possible biological names infered from orthology : Q9H4Y5
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: D1
Gene start: 47865545
Gene end: 47886324
  
Corresponding Affymetrix probe sets: 10463844 (MoGene1.0st)   1453708_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000119680
Ensembl peptide - ENSMUSP00000052592
Ensembl peptide - ENSMUSP00000113409
NCBI entrez gene - 68214     See in Manteia.
MGI - MGI:1915464
RefSeq - NM_026619
RefSeq - NM_030051
RefSeq Peptide - NP_080895
RefSeq Peptide - NP_084327
swissprot - D3Z1Q9
swissprot - Q8K2Q2
Ensembl - ENSMUSG00000025069
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gsto1ENSDARG00000022183Danio rerio
 gsto2ENSDARG00000033285Danio rerio
 GSTO1ENSGALG00000008409Gallus gallus
 GSTO2ENSG00000065621Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gsto1 / O09131 / Glutathione S-transferase omega-1 / P78417*ENSMUSG0000002506855


Protein motifs (from Interpro)
Interpro ID Name
 IPR004045  Glutathione S-transferase, N-terminal
 IPR005442  Glutathione S-transferase, omega-class
 IPR010987  Glutathione S-transferase, C-terminal-like
 IPR036249  Thioredoxin-like superfamily
 IPR036282  Glutathione S-transferase, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006749 glutathione metabolic process IBA
 biological_processGO:0006805 xenobiotic metabolic process ISO
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009407 toxin catabolic process IBA
 biological_processGO:0019852 L-ascorbic acid metabolic process ISO
 biological_processGO:0055114 oxidation-reduction process ISO
 biological_processGO:0071243 cellular response to arsenic-containing substance ISO
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004364 glutathione transferase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016491 oxidoreductase activity ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0045174 glutathione dehydrogenase (ascorbate) activity ISO
 molecular_functionGO:0050610 methylarsonate reductase activity IEA


Pathways (from Reactome)
Pathway description
Glutathione conjugation
Vitamin C (ascorbate) metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001284 absent vibrissae "missing whiskers" [J:18378]
Show

Allelic Composition: Nbeal2tm1a(EUCOMM)Wtsi/Nbeal2tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nbeal2tm1a(EUCOMM)Wtsi/Wtsi

 MP:0002833 increased heart weight "greater than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Nbeal2tm1a(EUCOMM)Wtsi/Nbeal2tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nbeal2tm1a(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000025069 Gsto2 / Q8K2Q2 / Glutathione S-transferase omega-2 / Q9H4Y5*  / complex






 

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contact: otassy@igbmc.fr