ENSG00000067829


Homo sapiens

Features
Gene ID: ENSG00000067829
  
Biological name :IDH3G
  
Synonyms : IDH3G / isocitrate dehydrogenase 3 (NAD(+)) gamma / P51553
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: q28
Gene start: 153785766
Gene end: 153794523
  
Corresponding Affymetrix probe sets: 202471_s_at (Human Genome U133 Plus 2.0 Array)   214333_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000401862
Ensembl peptide - ENSP00000402747
Ensembl peptide - ENSP00000482665
Ensembl peptide - ENSP00000408529
Ensembl peptide - ENSP00000217901
Ensembl peptide - ENSP00000359110
Ensembl peptide - ENSP00000359111
Ensembl peptide - ENSP00000400115
NCBI entrez gene - 3421     See in Manteia.
OMIM - 300089
RefSeq - NM_174869
RefSeq - NM_004135
RefSeq Peptide - NP_004126
RefSeq Peptide - NP_777358
swissprot - H7C1W2
swissprot - E9PF84
swissprot - P51553
swissprot - E7EQB8
swissprot - G5E9Q7
swissprot - H0Y5Q7
Ensembl - ENSG00000067829
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 idh3gENSDARG00000023648Danio rerio
 Idh3gENSMUSG00000002010Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IDH3B / O43837 / isocitrate dehydrogenase 3 (NAD(+)) betaENSG0000010136548


Protein motifs (from Interpro)
Interpro ID Name
 IPR004434  Isocitrate dehydrogenase NAD-dependent
 IPR019818  Isocitrate/isopropylmalate dehydrogenase, conserved site
 IPR024084  Isopropylmalate dehydrogenase-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process NAS
 biological_processGO:0006099 tricarboxylic acid cycle IEA
 biological_processGO:0006102 isocitrate metabolic process ISS
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004449 isocitrate dehydrogenase (NAD+) activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051287 NAD binding IEA


Pathways (from Reactome)
Pathway description
Mitochondrial protein import
Citric acid cycle (TCA cycle)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000166411 IDH3A / P50213 / isocitrate dehydrogenase 3 (NAD(+)) alpha  / complex
 ENSG00000101365 IDH3B / O43837 / isocitrate dehydrogenase 3 (NAD(+)) beta  / complex






 

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