ENSG00000069122


Homo sapiens

Features
Gene ID: ENSG00000069122
  
Biological name :ADGRF5
  
Synonyms : ADGRF5 / adhesion G protein-coupled receptor F5 / Q8IZF2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p12.3
Gene start: 46852512
Gene end: 46954943
  
Corresponding Affymetrix probe sets: 212950_at (Human Genome U133 Plus 2.0 Array)   212951_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000265417
Ensembl peptide - ENSP00000283296
NCBI entrez gene - 221395     See in Manteia.
RefSeq - XM_017010424
RefSeq - NM_001098518
RefSeq - NM_015234
RefSeq - XM_017010421
RefSeq - XM_017010422
RefSeq - XM_017010423
RefSeq - XM_005248892
RefSeq - XM_005248893
RefSeq - XM_005248894
RefSeq - XM_005248895
RefSeq - XM_011514353
RefSeq - XM_011514354
RefSeq - XM_017010418
RefSeq - XM_017010419
RefSeq - XM_017010420
RefSeq Peptide - NP_056049
RefSeq Peptide - NP_001091988
swissprot - Q8IZF2
Ensembl - ENSG00000069122
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000039320Gallus gallus
 Adgrf5ENSMUSG00000056492Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADGRF1 / Q5T601 / adhesion G protein-coupled receptor F1ENSG0000015329222
ADGRF3 / Q8IZF5 / adhesion G protein-coupled receptor F3ENSG0000017356720
ADGRF4 / Q8IZF3 / adhesion G protein-coupled receptor F4ENSG0000015329417
ADGRF2 / Q8IZF7 / adhesion G protein-coupled receptor F2ENSG0000016439317
ADGRB3 / O60242 / adhesion G protein-coupled receptor B3ENSG0000013529815
ADGRB2 / O60241 / adhesion G protein-coupled receptor B2ENSG0000012175315
ADGRB1 / O14514 / adhesion G protein-coupled receptor B1ENSG0000018179015
ADGRD2 / Q7Z7M1 / adhesion G protein-coupled receptor D2ENSG0000018026414
CFP / P27918 / complement factor properdinENSG000001267595


Protein motifs (from Interpro)
Interpro ID Name
 IPR000082  SEA domain
 IPR000203  GPS motif
 IPR000832  GPCR, family 2, secretin-like
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR008078  GPCR family 2, Ig-hepta-like receptor
 IPR013783  Immunoglobulin-like fold
 IPR017981  GPCR, family 2-like
 IPR017983  GPCR, family 2, secretin-like, conserved site
 IPR036179  Immunoglobulin-like domain superfamily
 IPR036364  SEA domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006112 energy reserve metabolic process IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0019216 regulation of lipid metabolic process IEA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0043031 negative regulation of macrophage activation IEA
 biological_processGO:0043129 surfactant homeostasis IEA
 biological_processGO:0045444 fat cell differentiation IEA
 biological_processGO:0071073 positive regulation of phospholipid biosynthetic process IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0031410 cytoplasmic vesicle IDA
 cellular_componentGO:0045177 apical part of cell IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity TAS


Pathways (from Reactome)
Pathway description
Surfactant metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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