ENSG00000121753


Homo sapiens

Features
Gene ID: ENSG00000121753
  
Biological name :ADGRB2
  
Synonyms : ADGRB2 / adhesion G protein-coupled receptor B2 / O60241
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p35.2
Gene start: 31727117
Gene end: 31764893
  
Corresponding Affymetrix probe sets: 204966_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000381550
Ensembl peptide - ENSP00000381548
Ensembl peptide - ENSP00000381555
Ensembl peptide - ENSP00000437219
Ensembl peptide - ENSP00000435397
Ensembl peptide - ENSP00000414758
Ensembl peptide - ENSP00000410921
Ensembl peptide - ENSP00000381564
Ensembl peptide - ENSP00000362759
Ensembl peptide - ENSP00000362762
NCBI entrez gene - 576     See in Manteia.
OMIM - 602683
RefSeq - XM_017001912
RefSeq - XM_017001903
RefSeq - XM_017001904
RefSeq - XM_017001905
RefSeq - XM_017001906
RefSeq - XM_017001907
RefSeq - XM_017001908
RefSeq - XM_017001909
RefSeq - XM_017001910
RefSeq - XM_017001911
RefSeq - NM_001294335
RefSeq - NM_001294336
RefSeq - XM_011541848
RefSeq - XM_011541849
RefSeq - XM_011541858
RefSeq - XM_017001899
RefSeq - XM_017001900
RefSeq - XM_017001901
RefSeq - XM_017001902
RefSeq Peptide - NP_001281264
RefSeq Peptide - NP_001281265
swissprot - A2A3C4
swissprot - A2A3C3
swissprot - E9PND1
swissprot - O60241
swissprot - A2A3C1
swissprot - A2A3C2
swissprot - A2A3C6
Ensembl - ENSG00000121753
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adgrb2ENSDARG00000025667Danio rerio
 ADGRB2ENSGALG00000043209Gallus gallus
 Adgrb2ENSMUSG00000028782Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADGRB3 / O60242 / adhesion G protein-coupled receptor B3ENSG0000013529848
ADGRB1 / O14514 / adhesion G protein-coupled receptor B1ENSG0000018179042
ADGRF5 / Q8IZF2 / adhesion G protein-coupled receptor F5ENSG0000006912212
ADGRF3 / Q8IZF5 / adhesion G protein-coupled receptor F3ENSG0000017356711
ADGRF1 / Q5T601 / adhesion G protein-coupled receptor F1ENSG0000015329210
ADGRD2 / Q7Z7M1 / adhesion G protein-coupled receptor D2ENSG000001802649
ADGRF4 / Q8IZF3 / adhesion G protein-coupled receptor F4ENSG000001532949
CFP / P27918 / complement factor properdinENSG000001267598
ADGRF2 / Q8IZF7 / adhesion G protein-coupled receptor F2ENSG000001643938


Protein motifs (from Interpro)
Interpro ID Name
 IPR000203  GPS motif
 IPR000832  GPCR, family 2, secretin-like
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR001879  GPCR, family 2, extracellular hormone receptor domain
 IPR008077  GPCR, family 2, brain-specific angiogenesis inhibitor
 IPR017981  GPCR, family 2-like
 IPR032471  GAIN domain, N-terminal
 IPR036383  Thrombospondin type-1 (TSP1) repeat superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007422 peripheral nervous system development IEA
 biological_processGO:0016525 negative regulation of angiogenesis IEA
 biological_processGO:0033173 calcineurin-NFAT signaling cascade IMP
 biological_processGO:0051965 positive regulation of synapse assembly IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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