ENSG00000181790


Homo sapiens

Features
Gene ID: ENSG00000181790
  
Biological name :ADGRB1
  
Synonyms : ADGRB1 / adhesion G protein-coupled receptor B1 / O14514
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: q24.3
Gene start: 142449430
Gene end: 142545009
  
Corresponding Affymetrix probe sets: 206083_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000494563
Ensembl peptide - ENSP00000313046
Ensembl peptide - ENSP00000427783
Ensembl peptide - ENSP00000430945
NCBI entrez gene - 575     See in Manteia.
OMIM - 602682
RefSeq - XM_017013697
RefSeq - NM_001702
RefSeq - XM_017013694
RefSeq - XM_017013695
RefSeq - XM_017013696
RefSeq - XM_011517199
RefSeq - XM_011517202
RefSeq - XM_017013691
RefSeq - XM_017013692
RefSeq - XM_017013693
RefSeq Peptide - NP_001693
swissprot - O14514
swissprot - E5RG74
Ensembl - ENSG00000181790
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adgrb1aENSDARG00000075133Danio rerio
 adgrb1bENSDARG00000078529Danio rerio
 ADGRB1ENSGALG00000033960Gallus gallus
 Adgrb1ENSMUSG00000034730Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADGRB3 / O60242 / adhesion G protein-coupled receptor B3ENSG0000013529847
ADGRB2 / O60241 / adhesion G protein-coupled receptor B2ENSG0000012175342
ADGRF5 / Q8IZF2 / adhesion G protein-coupled receptor F5ENSG0000006912213
ADGRF3 / Q8IZF5 / adhesion G protein-coupled receptor F3ENSG0000017356711
ADGRD2 / Q7Z7M1 / adhesion G protein-coupled receptor D2ENSG0000018026410
ADGRF1 / Q5T601 / adhesion G protein-coupled receptor F1ENSG0000015329210
CFP / P27918 / complement factor properdinENSG000001267599
ADGRF4 / Q8IZF3 / adhesion G protein-coupled receptor F4ENSG000001532948
ADGRF2 / Q8IZF7 / adhesion G protein-coupled receptor F2ENSG000001643938


Protein motifs (from Interpro)
Interpro ID Name
 IPR000203  GPS motif
 IPR000832  GPCR, family 2, secretin-like
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR001879  GPCR, family 2, extracellular hormone receptor domain
 IPR008077  GPCR, family 2, brain-specific angiogenesis inhibitor
 IPR017981  GPCR, family 2-like
 IPR032471  GAIN domain, N-terminal
 IPR036383  Thrombospondin type-1 (TSP1) repeat superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006909 phagocytosis IEA
 biological_processGO:0006910 phagocytosis, recognition ISS
 biological_processGO:0006911 phagocytosis, engulfment IEA
 biological_processGO:0007155 cell adhesion TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007409 axonogenesis TAS
 biological_processGO:0007422 peripheral nervous system development TAS
 biological_processGO:0007517 muscle organ development IEA
 biological_processGO:0008285 negative regulation of cell proliferation TAS
 biological_processGO:0010596 negative regulation of endothelial cell migration IDA
 biological_processGO:0016525 negative regulation of angiogenesis IDA
 biological_processGO:0031397 negative regulation of protein ubiquitination ISS
 biological_processGO:0042177 negative regulation of protein catabolic process ISS
 biological_processGO:0043277 apoptotic cell clearance IMP
 biological_processGO:0043652 engulfment of apoptotic cell ISS
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0048167 regulation of synaptic plasticity ISS
 biological_processGO:0050829 defense response to Gram-negative bacterium ISS
 biological_processGO:0051965 positive regulation of synapse assembly IEA
 biological_processGO:1901741 positive regulation of myoblast fusion ISS
 biological_processGO:1903428 positive regulation of reactive oxygen species biosynthetic process IMP
 cellular_componentGO:0001891 phagocytic cup ISS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0005911 cell-cell junction TAS
 cellular_componentGO:0005925 focal adhesion ISS
 cellular_componentGO:0014069 postsynaptic density ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043197 dendritic spine IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0001530 lipopolysaccharide binding ISS
 molecular_functionGO:0001786 phosphatidylserine binding ISS
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030165 PDZ domain binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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