ENSG00000135298


Homo sapiens

Features
Gene ID: ENSG00000135298
  
Biological name :ADGRB3
  
Synonyms : ADGRB3 / adhesion G protein-coupled receptor B3 / O60242
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: q12
Gene start: 68635367
Gene end: 69389511
  
Corresponding Affymetrix probe sets: 205638_at (Human Genome U133 Plus 2.0 Array)   211568_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000359630
Ensembl peptide - ENSP00000473827
Ensembl peptide - ENSP00000474165
Ensembl peptide - ENSP00000238918
Ensembl peptide - ENSP00000441821
NCBI entrez gene - 577     See in Manteia.
OMIM - 602684
RefSeq - XM_017011141
RefSeq - NM_001704
RefSeq - XM_006715534
RefSeq - XM_011536009
RefSeq - XM_011536010
RefSeq - XM_011536011
RefSeq - XM_017011140
RefSeq - XM_005248752
RefSeq Peptide - NP_001695
swissprot - O60242
swissprot - S4R307
swissprot - S4R3D0
swissprot - J3KMY8
Ensembl - ENSG00000135298
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adgrb3ENSDARG00000059832Danio rerio
 ENSGALG00000016176Gallus gallus
 ENSGALG00000030872Gallus gallus
 ENSGALG00000044704Gallus gallus
 Adgrb3ENSMUSG00000033569Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADGRB2 / O60241 / adhesion G protein-coupled receptor B2ENSG0000012175350
ADGRB1 / O14514 / adhesion G protein-coupled receptor B1ENSG0000018179049
ADGRF5 / Q8IZF2 / adhesion G protein-coupled receptor F5ENSG0000006912214
ADGRF3 / Q8IZF5 / adhesion G protein-coupled receptor F3ENSG0000017356711
ADGRF1 / Q5T601 / adhesion G protein-coupled receptor F1ENSG0000015329211
CFP / P27918 / complement factor properdinENSG000001267599
ADGRF2 / Q8IZF7 / adhesion G protein-coupled receptor F2ENSG000001643939
ADGRD2 / Q7Z7M1 / adhesion G protein-coupled receptor D2ENSG000001802649
ADGRF4 / Q8IZF3 / adhesion G protein-coupled receptor F4ENSG000001532949


Protein motifs (from Interpro)
Interpro ID Name
 IPR000203  GPS motif
 IPR000832  GPCR, family 2, secretin-like
 IPR000859  CUB domain
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR001879  GPCR, family 2, extracellular hormone receptor domain
 IPR008077  GPCR, family 2, brain-specific angiogenesis inhibitor
 IPR017981  GPCR, family 2-like
 IPR017983  GPCR, family 2, secretin-like, conserved site
 IPR032471  GAIN domain, N-terminal
 IPR036383  Thrombospondin type-1 (TSP1) repeat superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007520 myoblast fusion IDA
 biological_processGO:0016322 neuron remodeling IEA
 biological_processGO:0016525 negative regulation of angiogenesis IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0048814 regulation of dendrite morphogenesis ISS
 biological_processGO:0051965 positive regulation of synapse assembly IEA
 biological_processGO:0061743 motor learning IEA
 biological_processGO:0099558 maintenance of synapse structure IEA
 cellular_componentGO:0005886 plasma membrane IPI
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0043083 synaptic cleft IEA
 cellular_componentGO:0098794 postsynapse IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity TAS
 molecular_functionGO:0005096 GTPase activator activity ISS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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