ENSMUSG00000028782


Mus musculus

Features
Gene ID: ENSMUSG00000028782
  
Biological name :Adgrb2
  
Synonyms : Adgrb2 / Adhesion G protein-coupled receptor B2 / Q8CGM1
  
Possible biological names infered from orthology : O60241
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: D2.2
Gene start: 129984870
Gene end: 130022633
  
Corresponding Affymetrix probe sets: 10508500 (MoGene1.0st)   1435558_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000112869
Ensembl peptide - ENSMUSP00000101639
Ensembl peptide - ENSMUSP00000112524
Ensembl peptide - ENSMUSP00000030571
Ensembl peptide - ENSMUSP00000095480
Ensembl peptide - ENSMUSP00000101636
Ensembl peptide - ENSMUSP00000101638
NCBI entrez gene - 230775     See in Manteia.
MGI - MGI:2451244
RefSeq - XM_011240514
RefSeq - NM_173071
RefSeq - XM_011240506
RefSeq - XM_011240507
RefSeq - XM_011240508
RefSeq - XM_011240509
RefSeq - XM_011240510
RefSeq - XM_011240511
RefSeq - XM_011240512
RefSeq - XM_011240513
RefSeq - NM_001199696
RefSeq - NM_001290714
RefSeq - NM_001290715
RefSeq Peptide - NP_001277643
RefSeq Peptide - NP_001277644
RefSeq Peptide - NP_775094
RefSeq Peptide - NP_001186625
swissprot - H7BX74
swissprot - Q8CGM1
swissprot - H7BX92
swissprot - H7BWZ2
swissprot - B1ASC0
Ensembl - ENSMUSG00000028782
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adgrb2ENSDARG00000025667Danio rerio
 ADGRB2ENSGALG00000043209Gallus gallus
 ADGRB2ENSG00000121753Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Adgrb3 / Q80ZF8 / Adhesion G protein-coupled receptor B3 / O60242*ENSMUSG0000003356949
Adgrb1 / Q3UHD1 / Adhesion G protein-coupled receptor B1 Vasculostatin-120 Vasculostatin-40 / O14514* / adhesion G protein-coupled receptor B1*ENSMUSG0000003473042
Adgrf5 / G5E8Q8 / Mus musculus adhesion G protein-coupled receptor F5 (Adgrf5), transcript variant 2, mRNA. / Q8IZF2* / adhesion G protein-coupled receptor F5*ENSMUSG0000005649213
Adgrf3 / Q58Y75 / Adhesion G-protein coupled receptor F3 / Q8IZF5*ENSMUSG0000006764211
Adgrf1 / Q8VEC3 / Adhesion G-protein coupled receptor F1 / Q5T601*ENSMUSG0000004129311
Adgrf4 / adhesion G protein-coupled receptor F4 / Q8IZF3*ENSMUSG000000239189
Cfp / P11680 / complement factor properdin / P27918*ENSMUSG000000011288
Adgrf2 / E9Q4J9 / Adhesion G-protein coupled receptor F2 / Q8IZF7*ENSMUSG000000578998


Protein motifs (from Interpro)
Interpro ID Name
 IPR000203  GPS motif
 IPR000832  GPCR, family 2, secretin-like
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR001879  GPCR, family 2, extracellular hormone receptor domain
 IPR008077  GPCR, family 2, brain-specific angiogenesis inhibitor
 IPR017981  GPCR, family 2-like
 IPR032471  GAIN domain, N-terminal
 IPR036383  Thrombospondin type-1 (TSP1) repeat superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007422 peripheral nervous system development IDA
 biological_processGO:0016525 negative regulation of angiogenesis IEA
 biological_processGO:0033173 calcineurin-NFAT signaling cascade IEA
 biological_processGO:0051965 positive regulation of synapse assembly IDA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
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Allelic Composition: A830005F24Riktm1.1(KOMP)Mbp/A830005F24Rik+
Genetic Background: C57BL/6N-A830005F24Riktm1.1(KOMP)Mbp/Ucd

 MP:0003063 increased coping response "enhanced ability to respond productively to a stressful situation" [RGD:Rat Genome Database submission]
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Allelic Composition: C3ar1tm1Raw/C3ar1tm1Raw
Genetic Background: B6.129X1(B6)-C3ar1tm1Raw

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: A830005F24Riktm1.1(KOMP)Mbp/A830005F24Rik+
Genetic Background: C57BL/6N-A830005F24Riktm1.1(KOMP)Mbp/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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