ENSG00000073150


Homo sapiens

Features
Gene ID: ENSG00000073150
  
Biological name :PANX2
  
Synonyms : pannexin 2 / PANX2 / Q96RD6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q13.33
Gene start: 50170731
Gene end: 50180294
  
Corresponding Affymetrix probe sets: 1552944_a_at (Human Genome U133 Plus 2.0 Array)   239067_s_at (Human Genome U133 Plus 2.0 Array)   244471_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000379183
Ensembl peptide - ENSP00000159647
Ensembl peptide - ENSP00000384148
NCBI entrez gene - 56666     See in Manteia.
OMIM - 608421
RefSeq - NM_052839
RefSeq - NM_001160300
RefSeq Peptide - NP_001153772
RefSeq Peptide - NP_443071
swissprot - Q96RD6
swissprot - F8W8Y4
Ensembl - ENSG00000073150
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 panx2ENSDARG00000063019Danio rerio
 PANX2ENSGALG00000000003Gallus gallus
 Panx2ENSMUSG00000058441Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PANX3 / Q96QZ0 / pannexin 3ENSG0000015414315
PANX1 / Q96RD7 / pannexin 1ENSG0000011021813


Protein motifs (from Interpro)
Interpro ID Name
 IPR000990  Innexin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002931 response to ischemia IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006812 cation transport IBA
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0034214 protein hexamerization ISS
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0005921 gap junction IEA
 cellular_componentGO:0012505 endomembrane system IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0015267 channel activity IEA
 molecular_functionGO:0022829 wide pore channel activity IBA
 molecular_functionGO:0055077 gap junction hemi-channel activity ISS


Pathways (from Reactome)
Pathway description
Electric Transmission Across Gap Junctions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000073150 PANX2 / Q96RD6 / pannexin 2  / complex
 ENSG00000110218 PANX1 / Q96RD7 / pannexin 1  / complex






 

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