ENSG00000074660


Homo sapiens

Features
Gene ID: ENSG00000074660
  
Biological name :SCARF1
  
Synonyms : Q14162 / SCARF1 / scavenger receptor class F member 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p13.3
Gene start: 1633858
Gene end: 1645747
  
Corresponding Affymetrix probe sets: 1555021_a_at (Human Genome U133 Plus 2.0 Array)   206995_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000458174
Ensembl peptide - ENSP00000461468
Ensembl peptide - ENSP00000263071
Ensembl peptide - ENSP00000323964
Ensembl peptide - ENSP00000411167
NCBI entrez gene - 8578     See in Manteia.
OMIM - 607873
RefSeq - NM_145350
RefSeq - NM_003693
RefSeq Peptide - NP_003684
RefSeq Peptide - NP_663325
swissprot - Q14162
swissprot - A0A0A0MR54
swissprot - I3L4R9
Ensembl - ENSG00000074660
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 scarf1ENSDARG00000077285Danio rerio
 Q5ND28ENSMUSG00000038188Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96GP6 / SCARF2 / scavenger receptor class F member 2ENSG0000024448639
MEGF6 / O75095 / multiple EGF like domains 6ENSG0000016259126
PEAR1 / Q5VY43 / platelet endothelial aggregation receptor 1ENSG0000018780026
A6BM72 / MEGF11 / multiple EGF like domains 11ENSG0000015789025
MEGF10 / Q96KG7 / multiple EGF like domains 10ENSG0000014579425


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR002049  Laminin EGF domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR033329  Scavenger receptor class F member 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006707 cholesterol catabolic process IC
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0010976 positive regulation of neuron projection development ISS
 biological_processGO:0016322 neuron remodeling ISS
 biological_processGO:0016358 dendrite development IEA
 biological_processGO:0048680 positive regulation of axon regeneration ISS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030666 endocytic vesicle membrane TAS
 molecular_functionGO:0004888 transmembrane signaling receptor activity TAS
 molecular_functionGO:0005044 scavenger receptor activity IEA
 molecular_functionGO:0030169 low-density lipoprotein particle binding IDA


Pathways (from Reactome)
Pathway description
Scavenging by Class F Receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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